SCHEMBL110818

SCHEMBL110818

CC(=O)c1cc2c(cc1C)C(C)(C)C(C)CC2(C)C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARG P13631 8/20 0.52
RXRA P19793 18/20 0.42
RXRB P28702 11/20 0.42
RXRG P48443 10/20 0.42
RARB P10826 8/20 0.42
RARA P10276 4/20 0.42
CYP26A1 O43174 2/20 0.40
CYP26B1 Q9NR63 2/20 0.40
MEN1 O00255 1/20 0.40
ABCB11 O95342 1/20 0.40
ESR1 P03372 1/20 0.40
PGR P06401 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
CHRM1 P11229 1/20 0.40
DRD1 P21728 1/20 0.40
TBXA2R P21731 1/20 0.40
SLC6A2 P23975 1/20 0.40
ADRA1A P35348 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10689218 1.00 RARG (0.52) RARGRXRARXRBRXRGRARB
SCHEMBL23633279 1.00 RARG (0.52) RARGRXRARXRBRXRGRARB
SCHEMBL9299399 1.00 RARG (0.52) RARGRXRARXRBRXRGRARB
SCHEMBL29357179 1.00 RARG (0.52) RARGRXRARXRBRXRGRARB
SCHEMBL14414059 0.88 RARG (0.58) RARGRXRARXRBRXRGRARB
SCHEMBL8849445 0.88 RARG (0.43) RARGRXRARXRBRXRGRARB
SCHEMBL8356805 0.85 RARG (0.41) RARGRXRARXRBRXRGRARB
SCHEMBL4411079 0.84 RARG (0.49) RARGRXRARXRBRXRGRARB
SCHEMBL27845308 0.84 RARG (0.49) RARGRXRARXRBRXRGRARB
SCHEMBL14743868 0.84 RARG (0.41) RARGRXRARXRBRXRGRARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3858 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12589377-B2 Encapsulated composition comprising core-shell microcapsules and process for its preparation GIVAUDAN SA (CH) 2026-03-31 US claimed
EP-4695016-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2026-02-18 EP claimed
EP-4655373-A1 BIODEGRADABLE PERFUME COMPOSITION Givaudan SA (CH) 2025-12-03 EP claimed
US-20250344991-A1 COMPOSITIONS AND METHODS FOR A UNIVERSAL CLINICAL TEST FOR OLFACTORY DYSFUNCTION UNIV ROCKEFELLER (US) 2025-11-13 US claimed
US-20250302728-A1 FRAGRANCE COMPOSITIONS AND PRODUCTS CONVEYING A POSITIVE MOOD SYMRISE AG (DE) 2025-10-02 US claimed
EP-3648613-B1 COMPOSITIONS AND METHODS FOR A UNIVERSAL CLINICAL TEST FOR OLFACTORY DYSFUNCTION UNIV ROCKEFELLER (US) 2025-09-24 EP claimed
EP-4615941-A2 SUBSTITUTED 1,3-DIOXOLAN-4-ONES AND 1,3-DIOXAN-4-ONES AS FRAGRANCE INGREDIENTS BASF SE (DE) 2025-09-17 EP claimed
EP-4581114-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Novozymes A/S (DK) 2025-07-09 EP claimed
US-12338225-B2 2,2,6-trimethyl-4,5-dihydro-3H-oxepine as aroma ingredient BASF SE (DE) 2025-06-24 US claimed
CN-120202281-A Substituted 1, 3-dioxolan-4-ones and 1, 3-dioxane-4-ones as perfume ingredients 巴斯夫欧洲公司 2025-06-24 CN claimed
US-5354737-A Fragrance composition containing substantial amounts of acetyl hexamethyl tetralin, and deodorant composition containing the fragrance composition THE MENNEN COMPANY (US) 1994-10-11 US claimed
EP-0612726-A1 Peroxyacid and a process for the preparation of peroxyacids SOLVAY INTEROX LIMITED (GB) 1994-08-31 EP claimed
EP-0404470-B1 Fragrance compositions and their use in detergent products QUEST INT (NL) 1994-04-13 EP claimed
EP-0466237-B1 Stabilized emulsion systems QUEST INT (NL) 1994-03-23 EP claimed
EP-0565783-A1 Mixtures of acetylpolyalkylindanes and acetylpolyalkyltetralines PFW AROMA CHEMICALS B.V. (NL) 1993-10-20 EP claimed
EP-0561447-A1 Method of acylating 1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethylnaphthalene (HMT) and compositions comprising acylated HMT QUEST INTERNATIONAL B.V. (NL) 1993-09-22 EP claimed
US-5156766-A Nonionic emulsifiers, liquid hydrophobic system, perfumy stabilizer and other surfactants UNILEVER PATENT HOLDINGS, B.V. (NL) 1992-10-20 US claimed
EP-0466237-A1 Stabilized emulsion systems QUEST INTERNATIONAL B.V. (NL) 1992-01-15 EP claimed
EP-0404470-A1 Fragrance compositions and their use in detergent products QUEST INTERNATIONAL B.V. (NL) 1990-12-27 EP claimed
US-4284818-A Process for preparing hexamethyltetrahydronaphthalenes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-08-18 US claimed