Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 7/20 | 0.43 |
| ▸ | RXRA | P19793 | 15/20 | 0.37 |
| ▸ | RXRB | P28702 | 9/20 | 0.37 |
| ▸ | RXRG | P48443 | 9/20 | 0.37 |
| ▸ | RARB | P10826 | 6/20 | 0.37 |
| ▸ | RARA | P10276 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.35 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689218 | 0.88 | RARG (0.52) | RARGRXRARXRBRXRGRARB | |
| SCHEMBL9299399 | 0.88 | RARG (0.52) | RARGRXRARXRBRXRGRARB | |
| SCHEMBL29357179 | 0.88 | RARG (0.52) | RARGRXRARXRBRXRGRARB | |
| SCHEMBL23633279 | 0.88 | RARG (0.52) | RARGRXRARXRBRXRGRARB | |
| SCHEMBL110818 | 0.88 | RARG (0.52) | RARGRXRARXRBRXRGRARB | |
| SCHEMBL14414059 | 0.77 | RARG (0.58) | RARGRXRARXRBRXRGRARB | |
| SCHEMBL8849435 | 0.76 | TSHR (0.36) | RARG | |
| SCHEMBL14743868 | 0.76 | RARG (0.41) | RARGRXRARXRBRXRGRARB | |
| Benzyl Salicylate SCHEMBL8526684 | 0.75 | TDP1 (0.50) | RARGRXRARXRBRXRGRARB | |
| SCHEMBL8356805 | 0.74 | RARG (0.41) | RARGRXRARXRBRXRGRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561447-B1 | Method of acylating 1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethylnaphthalene (HMT) and compositions comprising acylated HMT | QUEST INT (NL) | 1997-01-02 | — | — | EP | disclosed |
| US-5430015-A | Acylation of tetralins | UNILEVER PATENT HOLDINGS, BV (NL) | 1995-07-04 | — | — | US | disclosed |
| EP-0561447-A1 | Method of acylating 1,2,3,4-tetrahydro-1,1,2,4,4,7-hexamethylnaphthalene (HMT) and compositions comprising acylated HMT | QUEST INTERNATIONAL B.V. (NL) | 1993-09-22 | — | — | EP | disclosed |