SCHEMBL8356805

SCHEMBL8356805

CC(=O)c1cc2c(cc1C)C(C)(C)C(C)CC2(C)C.CCCCCCCCCCCCC1CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARG P13631 3/20 0.41
PTGS1 P23219 2/20 0.36
PTGS2 P35354 2/20 0.36
RXRA P19793 9/20 0.36
RXRB P28702 4/20 0.36
RXRG P48443 4/20 0.36
CYP3A4 P08684 2/20 0.35
CYP2C8 P10632 2/20 0.35
S1PR3 Q99500 2/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RARA P10276 2/20 0.33
RARB P10826 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
S1PR1 P21453 4/20 0.32
S1PR4 O95977 1/20 0.32
S1PR5 Q9H228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL110818 0.85 RARG (0.52) RARGRXRARXRBRXRGRARA
SCHEMBL6234754 0.76 RARG (0.38) RARGRXRARXRBRXRGCYP3A4
SCHEMBL14414059 0.74 RARG (0.58) RARGRXRARXRBRXRGRARA
SCHEMBL4411079 0.74 RARG (0.49) RARGRXRARXRBRXRGRARA
SCHEMBL10685040 0.74 CYP26A1 (0.40) RARGRXRARXRBRXRGRARA
SCHEMBL14743868 0.73 RARG (0.41) RARGRXRARXRBRXRGRARA
SCHEMBL8849539 0.71 RARG (0.41) RARGRXRA
SCHEMBL8749985 0.69 RARG (0.42) RARGRXRARXRBRXRGRARA
SCHEMBL8056473 0.69 RARG (0.41) RARGRXRARXRBRXRGRARA
SCHEMBL9165996 0.68 RXRA (0.48) RARGRXRARXRBRXRGRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5919440-A HIGHLY VOLATILE PERFUME, IONE PERFUME, MUST, POLYMER PROCTER & GAMBLE COMPANY (US) 1999-07-06 US disclosed