Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
| ▸ | BAD | Q92934 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | HPN | P05981 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2564157 | 0.96 | MAPT (0.52) | BCL2L1BADMAPTTSHRALDH1A1 | |
| SCHEMBL668042 | 0.88 | MAPT (0.55) | BCL2L1BADMAPTTSHRALDH1A1 | |
| SCHEMBL19018589 | 0.85 | BCL2L1 (0.64) | BCL2L1BADMAPTTSHRALDH1A1 | |
| SCHEMBL34466372 | 0.78 | MAPT (0.50) | BCL2L1BADMAPTTSHRALDH1A1 | |
| SCHEMBL11610848 | 0.76 | TBXA2R (0.45) | BCL2L1BADMAPTTSHRALDH1A1 | |
| SCHEMBL12430502 | 0.76 | DYRK1A (0.46) | MAPTTSHRMAOAMAOBCYP2A6 | |
| SCHEMBL12430503 | 0.76 | SRD5A1 (0.46) | BCL2L1BADTSHRKMT2AMEN1 | |
| SCHEMBL12430518 | 0.76 | MAOA (0.44) | BCL2L1BADTSHRHSD17B10KMT2A | |
| SCHEMBL269511 | 0.76 | BCL2L1 (0.53) | BCL2L1BADMAPTTSHRALDH1A1 | |
| SCHEMBL12023190 | 0.75 | ALDH1A1 (0.54) | BCL2L1BADMAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435426-A | ADRENERGIC BLOCKING AGENTS, FROM A HYDROXY-KETONE, EPICHLOROHYDRIN AND AN AMINE | SOCIETE ANONYME DITE: SANOFI (FR) | 1984-03-06 | — | — | US | disclosed |