SCHEMBL11082064

SCHEMBL11082064

Cc1c(Cl)ccc(OCC(=O)Nc2ccccc2)c1C

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 2/20 0.63
HTT P42858 2/20 0.58
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
ALDH1A1 P00352 2/20 0.56
GBA1 P04062 1/20 0.56
MAPT P10636 1/20 0.56
NPC1 O15118 5/20 0.55
SMN1; SMN2 Q16637 1/20 0.54
CETP P11597 2/20 0.54
LMNA P02545 1/20 0.53
HPGD P15428 1/20 0.52
POLB P06746 3/20 0.52
RAB9A P51151 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
ATM Q13315 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10337637 0.90 NOTUM (0.62) NOTUMHTTMEN1KMT2AALDH1A1
SCHEMBL11071425 0.88 NOTUM (0.59) NOTUMHTTMEN1KMT2AALDH1A1
SCHEMBL11085038 0.85 MEN1 (0.54) MEN1KMT2AALDH1A1MAPTNPC1
SCHEMBL11081226 0.80 NOTUM (0.66) NOTUMHTTMEN1KMT2AALDH1A1
SCHEMBL10857636 0.80 NOTUM (0.70) NOTUMHTTMEN1KMT2AALDH1A1
SCHEMBL11086141 0.80 NOTUM (0.66) NOTUMHTTMEN1KMT2AALDH1A1
SCHEMBL27375947 0.80 MEN1 (0.61) MEN1KMT2AALDH1A1GBA1MAPT
SCHEMBL11082061 0.78 NOTUM (0.64) NOTUMHTTMEN1KMT2AALDH1A1
SCHEMBL11087457 0.78 CTSD (0.45) HTTMEN1KMT2AALDH1A1MAPT
SCHEMBL11087465 0.78 CTSD (0.45) HTTMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4465507-A Herbicidal acetanilides MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1984-08-14 US disclosed