SCHEMBL11086141

SCHEMBL11086141

Cc1cc(OCC(=O)Nc2ccccc2)c(C)cc1Cl

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.66
MEN1 O00255 4/20 0.64
KMT2A Q03164 4/20 0.64
MAPT P10636 3/20 0.64
HTT P42858 2/20 0.64
ALDH1A1 P00352 2/20 0.64
GBA1 P04062 1/20 0.64
POLB P06746 6/20 0.61
RAB9A P51151 4/20 0.61
NPC1 O15118 4/20 0.61
NPSR1 Q6W5P4 1/20 0.61
NFKB1 P19838 2/20 0.57
NFKB2 Q00653 2/20 0.57
RELA Q04206 2/20 0.57
SMN1; SMN2 Q16637 2/20 0.55
GALR3 O60755 1/20 0.55
MITF O75030 1/20 0.55
PAX8 Q06710 1/20 0.55
KLF5 Q13887 1/20 0.55
TDP1 Q9NUW8 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11081226 0.92 NOTUM (0.66) NOTUMMEN1KMT2AMAPTHTT
SCHEMBL11075247 0.86 MEN1 (0.56) MEN1KMT2AMAPTHTTALDH1A1
SCHEMBL10857636 0.84 NOTUM (0.70) NOTUMMEN1KMT2AMAPTHTT
SCHEMBL11074898 0.83 NOTUM (0.61) NOTUMMEN1KMT2AMAPTHTT
SCHEMBL11082061 0.83 NOTUM (0.64) NOTUMMEN1KMT2AMAPTHTT
SCHEMBL16063128 0.80 NOTUM (1.00) NOTUMMEN1KMT2AMAPTHTT
SCHEMBL11082064 0.80 NOTUM (0.63) NOTUMMEN1KMT2AMAPTHTT
SCHEMBL11075978 0.79 NPC1 (0.44) NOTUMMEN1KMT2AMAPTHTT
SCHEMBL11075971 0.79 NPC1 (0.44) NOTUMMEN1KMT2AMAPTHTT
SCHEMBL11084259 0.78 ALDH1A1 (0.57) MEN1KMT2AMAPTHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4465507-A Herbicidal acetanilides MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1984-08-14 US disclosed