Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11086325 | 0.83 | TP53 (0.45) | TP53SMN1; SMN2HBBDHFRPOLB | |
| SCHEMBL11599581 | 0.80 | TP53 (0.37) | TP53SMN1; SMN2HBBALDH1A1GRM2 | |
| SCHEMBL14453335 | 0.78 | TP53 (0.47) | TP53SMN1; SMN2HBBMAPTDHFR | |
| SCHEMBL1426468 | 0.77 | ELANE (0.48) | TP53SMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL21119006 | 0.76 | TP53 (0.64) | TP53SMN1; SMN2HBBALDH1A1CYP1A2 | |
| SCHEMBL21119007 | 0.76 | TP53 (0.64) | TP53SMN1; SMN2HBBALDH1A1CYP1A2 | |
| SCHEMBL10947307 | 0.76 | ALDH1A1 (0.42) | TP53SMN1; SMN2HBBALDH1A1CYP1A2 | |
| SCHEMBL31681885 | 0.75 | SMN1; SMN2 (0.43) | TP53SMN1; SMN2ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11076073 | 0.75 | TP53 (0.48) | TP53SMN1; SMN2HBBCYP1A2MAPT | |
| SCHEMBL11085438 | 0.75 | TP53 (0.41) | TP53SMN1; SMN2HBBCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459392-A | Method of making and polymer of heat resistant polyester using diglycidilhydantoins, diglycidiluracils, diglycidilbarbituric and isocyanuric acids | UNITIKA LIMITED (JP) | 1984-07-10 | — | — | US | disclosed |