Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573132 | 0.84 | L3MBTL1 (0.50) | ALDH1A1L3MBTL1POLBRAB9AKMT2A | |
| SCHEMBL22405000 | 0.84 | L3MBTL1 (0.50) | ALDH1A1L3MBTL1POLBRAB9AKMT2A | |
| SCHEMBL22534762 | 0.84 | L3MBTL1 (0.50) | ALDH1A1L3MBTL1POLBKDM4EMAPT | |
| SCHEMBL24156281 | 0.83 | KMT2A (0.50) | ALDH1A1L3MBTL1POLBRAB9AGRIN1 | |
| SCHEMBL11083601 | 0.83 | L3MBTL1 (0.49) | ALDH1A1L3MBTL1POLBRAB9AKMT2A | |
| SCHEMBL22405034 | 0.81 | MGLL (0.53) | ALDH1A1L3MBTL1POLBRAB9AKMT2A | |
| SCHEMBL30091779 | 0.81 | MGLL (0.53) | ALDH1A1L3MBTL1POLBRAB9AKMT2A | |
| SCHEMBL24155631 | 0.80 | EGFR (0.44) | ALDH1A1L3MBTL1POLBRAB9AKMT2A | |
| SCHEMBL24155843 | 0.80 | ALOX5AP (0.43) | ALDH1A1L3MBTL1POLBGRIN1GRIN2B | |
| SCHEMBL21399637 | 0.80 | HTT (0.67) | ALDH1A1L3MBTL1RXRAGRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4427437-A | PLANT GROWTH REGULATORS | ICI AUSTRALIA LIMITED (AU) | 1984-01-24 | — | — | US | disclosed |
| EP-0001187-B1 | 2-PHENOXY-PYRIMIDINES AND THEIR USE AS PESTICIDES | ICI AUSTRALIA LIMITED (AU) | 1983-12-07 | — | — | EP | disclosed |
| EP-0001187-A1 | 2-phenoxy-pyrimidines and their use as pesticides | ICI AUSTRALIA LIMITED (AU) | 1979-03-21 | — | — | EP | disclosed |