Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29617530 | 0.84 | IDO1 (0.50) | HTR6IDO1ALDH1A1CA1CA2 | |
| SCHEMBL9441442 | 0.84 | HTR6 (0.46) | HTR6IDO1ALDH1A1CA1CA2 | |
| SCHEMBL1793811 | 0.84 | HTR6 (0.46) | HTR6IDO1ALDH1A1CA1CA2 | |
| SCHEMBL28161613 | 0.84 | LMNA (0.47) | HTR6IDO1ALDH1A1CA1CA2 | |
| SCHEMBL1878272 | 0.84 | IDO1 (0.50) | HTR6IDO1ALDH1A1CA1CA2 | |
| SCHEMBL3698922 | 0.82 | HTR6 (0.45) | HTR6IDO1ALDH1A1CA1CA2 | |
| Zinc Ion SCHEMBL4882957 | 0.82 | HTR6 (0.49) | HTR6IDO1ALDH1A1CA1CA2 | |
| SCHEMBL3698920 | 0.82 | HTR6 (0.49) | HTR6IDO1ALDH1A1CA1CA2 | |
| SCHEMBL4885963 | 0.82 | HTR6 (0.49) | HTR6IDO1ALDH1A1CA1CA2 | |
| SCHEMBL3004774 | 0.82 | HTR6 (0.49) | HTR6IDO1ALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465506-A | Herbicidal N-[heterocyclicaminocarbonyl]-1H-indene and tetrahydronaphthalene sulfonamides | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1984-08-14 | — | — | US | disclosed |
| EP-0082681-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-06-29 | — | — | EP | disclosed |
| EP-0027906-B1 | PROCESS FOR PREPARING SULPHON AMIDES | BAYER AG (DE) | 1983-05-25 | — | — | EP | disclosed |
| EP-0027906-A1 | Process for preparing sulphon amides | BAYER AG (DE) | 1981-05-06 | — | — | EP | disclosed |