Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11082100 | 1.00 | CHRM2 (0.38) | CHRM2ALDH1A1TSHRL3MBTL3 | |
| SCHEMBL5949039 | 0.90 | CA1 (0.42) | ALDH1A1TSHR | |
| SCHEMBL12055776 | 0.90 | CA1 (0.35) | CHRM2ALDH1A1TSHR | |
| SCHEMBL794322 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TSHR | |
| SCHEMBL20281990 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TSHR | |
| SCHEMBL17589117 | 0.72 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL6535460 | 0.72 | MT-CO2 (0.46) | ALDH1A1TSHR | |
| SCHEMBL10719777 | 0.72 | MT-CO2 (0.46) | ALDH1A1TSHR | |
| SCHEMBL20384062 | 0.72 | CHRM2 (0.45) | CHRM2ALDH1A1L3MBTL3 | |
| SCHEMBL4374227 | 0.72 | MT-CO2 (0.46) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4480099-A | Decahydroquinolyl benzamides | BEECHAM GROUP P.L.C. (GB) | 1984-10-30 | — | — | US | disclosed |
| EP-0068699-A1 | Decahydroquinolyl benzamides, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1983-01-05 | — | — | EP | disclosed |