Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29463242 | 1.00 | LOXL2 (0.52) | LOXL2ALDH1A1HTTPNMTHRH3 | |
| SCHEMBL15228987 | 0.89 | LOXL2 (0.48) | LOXL2ALDH1A1HTTPNMTHRH3 | |
| SCHEMBL8357024 | 0.84 | TAAR1 (0.55) | LOXL2TAAR1 | |
| SCHEMBL631580 | 0.82 | TAAR1 (0.58) | ALDH1A1PNMTTAAR1DAO | |
| SCHEMBL21784991 | 0.81 | TAAR1 (0.62) | LOXL2HRH3TAAR1CYP17A1CYP11B1 | |
| SCHEMBL14451321 | 0.81 | TAAR1 (0.62) | LOXL2HRH3TAAR1CYP17A1CYP11B1 | |
| Hydrochloric Acid SCHEMBL1585557 | 0.80 | TAAR1 (0.56) | ALDH1A1PNMTTAAR1 | |
| SCHEMBL8281240 | 0.80 | LOXL2 (0.48) | LOXL2PNMTHRH3TAAR1ABAT | |
| SCHEMBL2007285 | 0.80 | LOXL2 (0.48) | LOXL2PNMTHRH3TAAR1ABAT | |
| SCHEMBL29467998 | 0.80 | LOXL2 (0.48) | LOXL2PNMTHRH3TAAR1ABAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1469 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117903168-A | Pyrrolo [2,3-d ] thiazole derivatives, and preparation method and application thereof | 南开大学 | 2024-04-19 | — | — | CN | claimed |
| EP-4069687-B1 | PROCESS AND INTERMEDIATES FOR THE PRODUCTION OF FORMULA (I) | ASTRAZENECA AB (SE) | 2024-01-31 | — | — | EP | claimed |
| US-20230046093-A1 | PROCESS AND INTERMEDIATES FOR THE PRODUCTION OF FORMULA (I) | ASTRAZENECA AB (SE) | 2023-02-16 | — | — | US | claimed |
| EP-4069687-A1 | PROCESS AND INTERMEDIATES FOR THE PRODUCTION OF FORMULA (I) | Astrazeneca AB (SE) | 2022-10-12 | — | — | EP | claimed |
| WO-2022131529-A1 | METHOD FOR MANUFACTURING THREE-DIMENSIONAL POROUS ELECTRODE STRUCTURE HAVING PROTECTIVE FILM FORMED BY ELECTRODEPOSITION COATING, THREE-DIMENSIONAL POROUS ELECTRODE STRUCTURE MANUFACTURED THEREBY, AND LITHIUM SECONDARY BATTERY COMPRISING SAME | 한국전기연구원 | 2022-06-23 | — | — | WO | claimed |
| CN-111410738-A | Preparation method of amine autocatalytic polyether polyol | 山东蓝星东大有限公司 | 2020-07-14 | — | — | CN | claimed |
| WO-2020018456-A1 | 2D PEROVSKITE STABILIZED PHASE-PURE FORMAMIDINIUM PEROVSKITE SOLAR CELLS AND LIGHT EMITTING DIODES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-01-23 | — | — | WO | claimed |
| EP-2819766-B1 | REMOVING SULPHUR OXIDES FROM A FLUID STREAM | BASF SE (DE) | 2016-05-18 | — | — | EP | claimed |
| EP-1363906-B1 | HETEROCYCLIC INHIBITORS OF ERK2 AND USES THEREOF | VERTEX PHARMA (US) | 2015-07-15 | — | — | EP | claimed |
| EP-2819766-A1 | REMOVING SULPHUR OXIDES FROM A FLUID STREAM | BASF SE (DE) | 2015-01-07 | — | — | EP | claimed |
| EP-1422218-A1 | ANTIVIRAL AGENT | SHIONOGI & CO., LTD. (JP) | 2004-05-26 | — | — | EP | claimed |
| EP-1155001-A4 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | LION BIOSCIENCE AG (DE) | 2003-05-28 | — | — | EP | claimed |
| US-6417195-B1 | LIBRARIES AND COMBINATORIAL CHEMISTRY | LION BIOSCIENCE AG (DE) | 2002-07-09 | — | — | US | claimed |
| EP-1155001-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 2001-11-21 | — | — | EP | claimed |
| WO-2000050406-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | LION BIOSCIENCE AG (DE) | 2000-08-31 | — | — | WO | claimed |
| EP-0863877-A4 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INST (US) | 1999-07-21 | — | — | EP | claimed |
| US-5874443-A | BIOSYNTHESIS | TREGA BIOSCIENCES, INC. (US) | 1999-02-23 | — | — | US | claimed |
| CN-1202888-A | Isoquinoline derivatives and isoquinoline combinatorial libraries | TORREY PINES INST (US) | 1998-12-23 | — | — | CN | claimed |
| EP-0863877-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1998-09-16 | — | — | EP | claimed |
| WO-1997016428-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-05-09 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230046093-A1 | PROCESS AND INTERMEDIATES FOR THE PRODUCTION OF FORMULA (I) | CYP2F1, CYP11B1, CYP4F11 | LOXL2 3555/4885ALDH1A1 306/4885HTT 4033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.