Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563067 | 0.86 | TAAR1 (0.52) | TAAR1MAOBPNMTCYP2A6 | |
| Hydrochloric Acid SCHEMBL6563097 | 0.85 | TAAR1 (0.50) | TAAR1MAOBPNMT | |
| SCHEMBL2389571 | 0.85 | TAAR1 (0.45) | LOXL2TAAR1IDO1AGXTCYP2A6 | |
| SCHEMBL2948434 | 0.85 | CYP4F2 (0.40) | LOXL2TAAR1IDO1AGXTABAT | |
| SCHEMBL1695325 | 0.85 | CSNK2A1 (0.45) | LOXL2TAAR1HRH3MAOB | |
| SCHEMBL18562850 | 0.85 | LOXL2 (0.43) | LOXL2TAAR1HRH3MAOBIDO1 | |
| SCHEMBL6564877 | 0.83 | CYP2D6 (0.41) | LOXL2TAAR1PNMTCYP2A6 | |
| SCHEMBL25240608 | 0.81 | LOXL2 (0.40) | LOXL2TAAR1HRH3MAOBIDO1 | |
| SCHEMBL25217284 | 0.81 | LOXL2 (0.37) | LOXL2TAAR1MAOBIDO1AGXT | |
| Hydrochloric Acid SCHEMBL6563201 | 0.81 | CYP1A2 (0.40) | LOXL2TAAR1MAOBIDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8715635-B2 | Frictionless molecular rotary motors | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-05-06 | — | — | US | disclosed |
| US-8715635-B2 | Frictionless molecular rotary motors | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2014-05-06 | — | — | US | disclosed |
| CN-102557879-A | Preparation method for 1,4-di(hydroxy methyl)-2-fluorobenzene | SHANGHAI SINOFLUORO SCIENT CO | 2012-07-11 | — | — | CN | disclosed |
| CN-102531847-A | Method for preparing 4-methyl-3-fluorobenzyl alcohol | SHANGHAI SINOFLUORO SCIENT CO | 2012-07-04 | — | — | CN | disclosed |
| US-7964633-B2 | such as N,N'-[hexane-1,6-diylbis(iminocarbonyl)]bis(3-chlorobenzenesulfonamide), used as Fructose-1,6-bisphosphatase inhibitors; metabolic disorders such as diabetes | HOFFMANN-LA ROCHE INC. (US) | 2011-06-21 | — | — | US | disclosed |
| EP-2081889-B1 | SULFONAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2010-12-22 | — | — | EP | disclosed |
| US-20100016610-A1 | FRICTIONLESS MOLECULAR ROTARY MOTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2010-01-21 | — | — | US | disclosed |
| EP-2081889-A1 | SULFONAMIDE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008096360-A2 | FRICTIONLESS MOLECULAR ROTARY MOTORS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2008-08-14 | — | — | WO | disclosed |
| US-20080085928-A1 | Sulfonamide derivatives | HOFFMANN-LA ROCHE INC. | 2008-04-10 | — | — | US | disclosed |
| WO-2008037628-A1 | SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080085928-A1 | Sulfonamide derivatives | SULT2A1, SULT1A1, SULT1E1 | LOXL2 2708/4885TAAR1 1945/4885HRH3 1858/4885 |
| US-20100016610-A1 | FRICTIONLESS MOLECULAR ROTARY MOTORS | DYNLL2, ATXN2L, DYNLL1 | LOXL2 3736/4885TAAR1 3402/4885HRH3 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.