Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | GLS | O94925 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087924 | 0.97 | EPHX2 (0.64) | EPHX2GLSMEN1KMT2AHDAC8 | |
| SCHEMBL11079169 | 0.95 | EPHX2 (0.67) | EPHX2GLSMEN1KMT2AHDAC8 | |
| SCHEMBL11085609 | 0.83 | EPHX2 (0.58) | EPHX2GLSMEN1KMT2AHDAC8 | |
| SCHEMBL4992517 | 0.81 | EPHX2 (0.50) | EPHX2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL6385132 | 0.81 | EPHX2 (0.64) | EPHX2GLSMEN1KMT2AHDAC8 | |
| SCHEMBL5049597 | 0.80 | EPHX2 (0.90) | EPHX2MEN1KMT2AHDAC8HDAC6 | |
| SCHEMBL9637883 | 0.79 | EPHX2 (0.62) | EPHX2GLSMEN1KMT2AHDAC8 | |
| SCHEMBL11079215 | 0.79 | EPHX2 (0.62) | EPHX2GLSMEN1KMT2AHDAC8 | |
| SCHEMBL5896895 | 0.79 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5897658 | 0.79 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460600-A | Adjacently substituted ketal derivatives of cycloalkane-amide analgesics | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |