Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GLS | O94925 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6385132 | 0.83 | EPHX2 (0.64) | EPHX2MEN1KMT2AALDH1A1GLS | |
| SCHEMBL11087924 | 0.83 | EPHX2 (0.64) | EPHX2MEN1KMT2AALDH1A1GLS | |
| SCHEMBL11079215 | 0.81 | EPHX2 (0.62) | EPHX2MEN1KMT2AALDH1A1GLS | |
| SCHEMBL11079169 | 0.81 | EPHX2 (0.67) | EPHX2MEN1KMT2AALDH1A1GLS | |
| SCHEMBL7848641 | 0.81 | LMNA (0.46) | EPHX2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11077879 | 0.80 | EPHX2 (0.65) | EPHX2MEN1KMT2AALDH1A1GLS | |
| SCHEMBL28857728 | 0.80 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1 | |
| SCHEMBL1008551 | 0.80 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1 | |
| SCHEMBL11083024 | 0.79 | EPHX2 (0.59) | EPHX2MEN1KMT2AALDH1A1GLS | |
| SCHEMBL14472842 | 0.79 | EPHX1 (0.67) | EPHX2MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5109008-A | Analgesics, diuretics, antiischemic agents | GLAXO GROUP LIMITED (GB) | 1992-04-28 | — | — | US | disclosed |
| EP-0366327-A1 | Furo- and thieno[3,2-c]pyridines and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1990-05-02 | — | — | EP | disclosed |
| EP-0176309-A3 | USE OF N-(2-AMINOCYCLOHEXYL)BENZENEACETAMIDES IN THE TREATMENT OF CEREBRAL ISCHEMIA | THE UPJOHN COMPANY (US) | 1987-11-25 | — | — | EP | disclosed |
| EP-0176309-A3 | USE OF N-(2-AMINOCYCLOHEXYL)BENZENEACETAMIDES IN THE TREATMENT OF CEREBRAL ISCHEMIA | THE UPJOHN COMPANY (US) | 1987-11-25 | — | — | EP | disclosed |
| US-4618621-A | SUBSTITUTED CYCLOHEXYLBENZENEACETAMIDE | THE UPJOHN COMPANY (US) | 1986-10-21 | — | — | US | disclosed |
| US-4588591-A | Analgesic 2-oxa-spirocyclic compounds | THE UPJOHN COMPANY (US) | 1986-05-13 | — | — | US | disclosed |
| EP-0176309-A2 | Use of N-(2-aminocyclohexyl)benzeneacetamides in the treatment of cerebral ischemia | THE UPJOHN COMPANY (US) | 1986-04-02 | — | — | EP | disclosed |
| EP-0176309-A2 | Use of N-(2-aminocyclohexyl)benzeneacetamides in the treatment of cerebral ischemia | THE UPJOHN COMPANY (US) | 1986-04-02 | — | — | EP | disclosed |
| EP-0176309-A2 | Use of N-(2-aminocyclohexyl)benzeneacetamides in the treatment of cerebral ischemia | THE UPJOHN COMPANY (US) | 1986-04-02 | — | — | EP | disclosed |
| US-4463013-A | Oxygen substituted amino-cyclohexyl-benzeneacetamides and -benzamides as water diuretic drugs | THE UPJOHN COMPANY (US) | 1984-07-31 | — | — | US | disclosed |