Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | INSR | P06213 | 2/20 | 0.55 |
| ▸ | IGF1R | P08069 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MYC | P01106 | 1/20 | 0.54 |
| ▸ | MAX | P61244 | 1/20 | 0.54 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.52 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083053 | 1.00 | MEN1 (0.55) | MEN1POLBHPGDKMT2AL3MBTL1 | |
| SCHEMBL622884 | 0.79 | INSR (0.69) | INSRIGF1RMYCMAXPIM1 | |
| SCHEMBL622883 | 0.79 | INSR (0.69) | INSRIGF1RMYCMAXPIM1 | |
| SCHEMBL622882 | 0.79 | INSR (0.69) | INSRIGF1RMYCMAXPIM1 | |
| SCHEMBL8115898 | 0.78 | MEN1 (0.65) | MEN1POLBHPGDKMT2AL3MBTL1 | |
| SCHEMBL8176812 | 0.78 | MEN1 (0.65) | MEN1POLBHPGDKMT2AL3MBTL1 | |
| SCHEMBL8115897 | 0.78 | MEN1 (0.65) | MEN1POLBHPGDKMT2AL3MBTL1 | |
| SCHEMBL12297879 | 0.77 | RXRA (0.82) | MEN1POLBHPGDKMT2AL3MBTL1 | |
| SCHEMBL3904208 | 0.76 | IGF1R (0.79) | MEN1POLBHPGDKMT2AL3MBTL1 | |
| SCHEMBL3904205 | 0.76 | IGF1R (0.79) | MEN1POLBHPGDKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439443-A | REDUCE HEMORRHAGE WITH MERCAPTO THIENYL ACRYLIC ACIDS OR DISULFIDES | RICHARDSON-MERRELL INC. (US) | 1984-03-27 | — | — | US | disclosed |
| US-4347255-A | REDUCING HEMORRHAGE AND NECROSIS WITH ALPHA-MERCAPTO-BETA-HETERO ACRYLIC ACIDS AND DISULFIDES | RICHARDSON-MERRELL INC. (US) | 1982-08-31 | — | — | US | disclosed |
| US-4169149-A | Use of α-mercapto-β-arylacrylic acid derivatives in heavy metal poisoning | GIROUX EUGENE L | 1979-09-25 | — | — | US | disclosed |
| US-4130653-A | 2-MERCAPTO-3-ARYL ACRYLIC ACID | MERRELL TORAUDE ET COMPAGNIE (FR) | 1978-12-19 | — | — | US | disclosed |
| US-4124718-A | ADMINISTERING A-MERCAPTO-B-ARYL-ACRYLIC ACIDS | MERRELL TORAUDE ET COMPAGNIE (FR) | 1978-11-07 | — | — | US | disclosed |