Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13558679 | 0.89 | KMT2A (0.53) | LMNAKMT2AALDH1A1ALOX15TSHR | |
| SCHEMBL140123 | 0.87 | KMT2A (0.61) | LMNAKMT2AALDH1A1ALOX15TSHR | |
| SCHEMBL17564538 | 0.86 | CA12 (0.54) | LMNAKMT2ACA12CA1CA2 | |
| SCHEMBL11374223 | 0.86 | LMNA (0.45) | LMNAKMT2AALDH1A1ALOX15TSHR | |
| SCHEMBL6272889 | 0.85 | KMT2A (0.48) | LMNAKMT2AALDH1A1ALOX15TSHR | |
| SCHEMBL9188023 | 0.85 | KMT2A (0.65) | LMNAKMT2AALDH1A1CA12CA1 | |
| SCHEMBL7099893 | 0.85 | KMT2A (0.69) | LMNAKMT2ACA12CA1CA2 | |
| SCHEMBL7519862 | 0.85 | LMNA (0.48) | LMNAKMT2AALDH1A1ALOX15TSHR | |
| SCHEMBL9357110 | 0.81 | KMT2A (0.61) | LMNAKMT2ACA12CA1CA2 | |
| SCHEMBL17564535 | 0.81 | KMT2A (0.47) | LMNAKMT2AALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4433145-A | HEAT AND LIGHT STABILIZERS FOR POLYMERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-21 | — | — | US | disclosed |