SCHEMBL7519862

SCHEMBL7519862

NCCNc1nc(Cl)nc(Cl)n1

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
CA12 O43570 4/20 0.45
CA1 P00915 4/20 0.45
CA2 P00918 4/20 0.45
CA9 Q16790 4/20 0.45
CA14 Q9ULX7 3/20 0.45
KMT2A Q03164 3/20 0.44
NR1I2 O75469 1/20 0.40
AHR P35869 1/20 0.40
ALDH1A1 P00352 1/20 0.38
ALOX15 P16050 1/20 0.38
TSHR P16473 1/20 0.38
CA5A P35218 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
STK17A Q9UEE5 1/20 0.36
PKM P14618 1/20 0.36
RAD52 P43351 1/20 0.36
CXCR4 P61073 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17564538 0.86 CA12 (0.54) LMNACA12CA1CA2CA9
SCHEMBL17564588 0.86 LMNA (0.73) LMNAKMT2ANR1I2AHRPKM
SCHEMBL11083082 0.85 LMNA (0.56) LMNACA12CA1CA2CA9
SCHEMBL430482 0.82 CXCR4 (0.40) LMNACA12CA1CA2CA9
SCHEMBL8367694 0.81 CYP1A2 (0.49) LMNACA12CA1CA2CA9
SCHEMBL18466745 0.81 KMT2A (0.42) LMNACA12CA1CA2CA9
SCHEMBL13558679 0.80 KMT2A (0.53) LMNACA12CA1CA2CA9
SCHEMBL20053796 0.80 KMT2A (0.58) LMNACA12CA1CA2CA9
SCHEMBL17564594 0.80 KMT2A (0.71) LMNACA12CA1CA2CA9
SCHEMBL12373451 0.79 KMT2A (0.57) LMNACA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1908292-A Cellulose fiber and fireproof application of goods containing same DEGUSSA (DE) 2007-02-07 CN claimed
US-20020037410-A1 Using a 4, 6-dichloro-1,3,5-triazine-2-yl amine compounds; permanent flameproofing; washfastness DEGUSSA AG (DE) 2002-03-28 US claimed
WO-2016036847-A9 SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME BATTELLE MEMORIAL INSTITUTE (US) 2017-04-20 WO disclosed
US-9562137-B2 Synthetic polymers and methods of making and using the same BATTELLE MEMORIAL INSTITUTE (US) 2017-02-07 US disclosed
US-9562137-B2 Synthetic polymers and methods of making and using the same BATTELLE MEMORIAL INSTITUTE (US) 2017-02-07 US disclosed
US-20160257785-A1 SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME U.S. DEPARTMENT OF ENERGY 2016-09-08 US disclosed
US-20160257785-A1 SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME U.S. DEPARTMENT OF ENERGY 2016-09-08 US disclosed
US-9365676-B2 Synthetic polymers and methods of making and using the same BATTELLE MEMORIAL INSTITUTE (US) 2016-06-14 US disclosed
US-9365676-B2 Synthetic polymers and methods of making and using the same BATTELLE MEMORIAL INSTITUTE (US) 2016-06-14 US disclosed
US-20160068635-A1 SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME BATTELLE MEMORIAL INSTITUTE 2016-03-10 US disclosed
US-20160068635-A1 SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME BATTELLE MEMORIAL INSTITUTE 2016-03-10 US disclosed
WO-2016036847-A1 SYNTHETIC POLYMERS AND METHODS OF MAKING AND USING THE SAME BATTELLE MEMORIAL INSTITUTE (US) 2016-03-10 WO disclosed
US-20020037410-A1 Using a 4, 6-dichloro-1,3,5-triazine-2-yl amine compounds; permanent flameproofing; washfastness DEGUSSA AG (DE) 2002-03-28 US disclosed