Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11080625 | 0.88 | TSHR (0.42) | SLC6A9SLC6A5TSHR | |
| SCHEMBL11083150 | 0.84 | SLC6A9 (0.38) | SLC6A9SLC6A5TSHRHSD11B1 | |
| SCHEMBL7280219 | 0.81 | SLC6A9 (0.44) | SLC6A9SLC6A5TSHR | |
| SCHEMBL11074848 | 0.74 | NPSR1 (0.38) | SLC6A9 | |
| SCHEMBL11082562 | 0.74 | TSHR (0.42) | SLC6A9TSHR | |
| SCHEMBL7286171 | 0.73 | MEN1 (0.42) | — | |
| SCHEMBL11080632 | 0.72 | TSHR (0.44) | SLC6A9SLC6A5TSHR | |
| SCHEMBL11078367 | 0.72 | CA12 (0.48) | — | |
| SCHEMBL11074855 | 0.71 | NPSR1 (0.41) | SLC6A9 | |
| SCHEMBL7280392 | 0.70 | SLC6A2 (0.41) | SLC6A9SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440941-A | Aroyl-aminoacids, amides and esters thereof | USV PHARMACEUTICAL CORPORATION (US) | 1984-04-03 | — | — | US | disclosed |