Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286171 | 0.85 | MEN1 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7280219 | 0.84 | SLC6A9 (0.44) | SLC6A2SLC6A4SLC6A3SLC6A9SLC6A5 | |
| SCHEMBL7291138 | 0.83 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL7277786 | 0.81 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3CHRM4CYP3A4 | |
| SCHEMBL7287426 | 0.74 | CA12 (0.49) | — | |
| SCHEMBL7287639 | 0.74 | MEN1 (0.38) | SLC6A2SLC6A4SLC6A3SLC6A9SLC6A5 | |
| SCHEMBL11080625 | 0.73 | TSHR (0.42) | SLC6A9SLC6A5 | |
| SCHEMBL7277297 | 0.73 | SLC6A9 (0.41) | SLC6A2SLC6A4SLC6A3KCNH2SLC6A9 | |
| SCHEMBL7286178 | 0.72 | MEN1 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7280229 | 0.71 | SLC6A9 (0.47) | SLC6A2SLC6A4SLC6A3KCNH2SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440941-A | Aroyl-aminoacids, amides and esters thereof | USV PHARMACEUTICAL CORPORATION (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0054936-A1 | Aroyl amino acids | USV PHARMACEUTICAL CORPORATION (US) | 1982-06-30 | — | — | EP | disclosed |