Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16828009 | 0.85 | MAPKAPK2 (0.42) | ALDH1A1GABRA1GABRG2GABRB3HTR6 | |
| SCHEMBL16827960 | 0.80 | RXFP1 (0.43) | CHRNB2CHRNA4HTR6MAP3K5HTR2C | |
| SCHEMBL6039509 | 0.75 | NSD3 (0.43) | NSD3ALDH1A1CHRNB2CHRNA4GABRA1 | |
| SCHEMBL27035794 | 0.75 | JAK2 (0.38) | NSD3ALDH1A1CHRNB2CHRNA4GABRA1 | |
| SCHEMBL11081607 | 0.74 | ACHE (0.50) | SIGMAR1HTR2CHTR2A | |
| SCHEMBL1544804 | 0.73 | MAPK13 (0.44) | L3MBTL1GABRG2GABRB3GABRA5MAP3K5 | |
| SCHEMBL24185331 | 0.72 | MAP3K5 (0.40) | L3MBTL1ALDH1A1MAP3K5 | |
| SCHEMBL22126011 | 0.72 | TNF (0.38) | ALDH1A1MAP3K5 | |
| SCHEMBL16828058 | 0.72 | CHRNB2 (0.42) | NSD3CHRNB2CHRNA4GABRA1GABRB2 | |
| SCHEMBL5634958 | 0.72 | NSD3 (0.46) | NSD3CHRNB2CHRNA4GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481360-A | 4H-1,2,4-Triazol-3-yl compounds | THE UPJOHN COMPANY (US) | 1984-11-06 | — | — | US | disclosed |