Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11194822 | 0.83 | ALDH1A1 (0.52) | ALDH1A1TDP1MAPTHCAR3HTT | |
| SCHEMBL11092141 | 0.81 | KMT2A (0.49) | ALDH1A1TDP1MAPTHTTNPC1 | |
| SCHEMBL29872530 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRS100A4GPR35 | |
| SCHEMBL9559517 | 0.81 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRS100A4GPR35 | |
| SCHEMBL11057023 | 0.79 | ALDH1A1 (0.50) | ALDH1A1TDP1MAPTHTTTSHR | |
| SCHEMBL5780946 | 0.78 | ALDH1A1 (0.45) | ALDH1A1TDP1MAPTHTTTSHR | |
| SCHEMBL472796 | 0.76 | TSHR (0.55) | ALDH1A1TDP1MAPTTSHRS100A4 | |
| SCHEMBL11095118 | 0.76 | SMN1; SMN2 (0.52) | ALDH1A1TDP1MAPTRECQLHSD17B10 | |
| SCHEMBL2371812 | 0.74 | TSHR (0.52) | ALDH1A1TDP1HTTTSHRS100A4 | |
| SCHEMBL19899520 | 0.74 | ALDH1A1 (0.67) | ALDH1A1TDP1MAPTTSHRKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473374-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1984-09-25 | — | — | US | disclosed |
| US-4330291-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-05-18 | — | — | US | disclosed |