Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23924910 | 0.85 | KMT2A (0.50) | KMT2AMAPTNPSR1ALDH1A1HTT | |
| SCHEMBL8512483 | 0.83 | KMT2A (0.45) | KMT2AMAPTNPSR1ALDH1A1HTT | |
| SCHEMBL30623145 | 0.83 | KMT2A (0.45) | KMT2AMAPTNPSR1ALDH1A1HTT | |
| SCHEMBL21486767 | 0.83 | RXFP1 (0.47) | KMT2AMAPTNPSR1ALDH1A1HTT | |
| SCHEMBL11094360 | 0.83 | KMT2A (0.45) | KMT2AMAPTNPSR1ALDH1A1HTT | |
| SCHEMBL10969677 | 0.82 | KMT2A (0.47) | KMT2AMAPTNPSR1ALDH1A1HTT | |
| SCHEMBL11083281 | 0.81 | ALDH1A1 (0.42) | KMT2AMAPTNPSR1ALDH1A1HTT | |
| SCHEMBL11095118 | 0.81 | SMN1; SMN2 (0.52) | KMT2AMAPTALDH1A1HPGDPOLB | |
| SCHEMBL23925201 | 0.80 | KMT2A (0.52) | KMT2AMAPTNPSR1ALDH1A1HTT | |
| SCHEMBL7414257 | 0.79 | SMN1; SMN2 (0.46) | KMT2AMAPTNPSR1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473374-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1984-09-25 | — | — | US | disclosed |
| US-4330291-A | Nitrated coupler compounds useful in direct dyeing and simultaneous oxidation and direct dyeing of keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-05-18 | — | — | US | disclosed |