Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | STAT6 | P42226 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090074 | 0.87 | NPSR1 (0.54) | JAK3ALDH1A1GAASTAT6MAPK8 | |
| SCHEMBL11082372 | 0.83 | KDM4E (0.58) | JAK3ALDH1A1GAAKDM4EADORA3 | |
| SCHEMBL25435416 | 0.81 | JAK3 (0.51) | JAK3ALDH1A1GAATSHRNFKB1 | |
| SCHEMBL15358319 | 0.78 | ATM (0.49) | GAATSHRSTAT6 | |
| SCHEMBL10493046 | 0.77 | ATM (0.59) | ALDH1A1STAT6MAPK8HPGDKDM4E | |
| SCHEMBL11089737 | 0.76 | VNN1 (0.55) | JAK3ALDH1A1STAT6ADORA3 | |
| SCHEMBL15358464 | 0.76 | P4HTM (0.53) | JAK3STAT6KMT2AMAPTCYP1A2 | |
| SCHEMBL16346217 | 0.75 | PDE5A (0.57) | — | |
| SCHEMBL15358452 | 0.75 | HDAC3 (0.57) | JAK3STAT6 | |
| SCHEMBL22261168 | 0.73 | JAK3 (0.62) | JAK3ALDH1A1GAASTAT6MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447422-A | Penicillins and compositions containing them | BEECHAM GROUP P.1.C. (GB) | 1984-05-08 | — | — | US | disclosed |
| EP-0067610-A1 | Penicillins, a process for their preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | disclosed |