Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | JAK3 | P52333 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | PDE5A | O76074 | 3/20 | 0.45 |
| ▸ | PDE6D | O43924 | 1/20 | 0.45 |
| ▸ | PDE6A | P16499 | 1/20 | 0.45 |
| ▸ | PDE6G | P18545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083552 | 0.87 | JAK3 (0.52) | POLBKMT2AMEN1JAK3STAT6 | |
| SCHEMBL11084827 | 0.84 | RAB9A (0.61) | NPSR1RAB9AJAK3ADORA3ADORA2A | |
| SCHEMBL11090652 | 0.81 | MAPT (0.62) | NPSR1RAB9APOLBKMT2AMEN1 | |
| SCHEMBL11088479 | 0.81 | NPSR1 (0.80) | NPSR1RAB9APOLBKMT2AMEN1 | |
| SCHEMBL16345647 | 0.77 | PDE5A (0.62) | NPSR1RAB9APOLBKMT2AMEN1 | |
| SCHEMBL11090716 | 0.75 | RAB9A (0.53) | NPSR1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL11240835 | 0.75 | HSD17B2 (0.65) | RAB9APOLBKMT2AMEN1HSD17B2 | |
| SCHEMBL11091988 | 0.75 | ALDH1A1 (0.59) | NPSR1RAB9AKMT2AMEN1JAK3 | |
| SCHEMBL11092599 | 0.74 | RAB9A (0.50) | NPSR1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL11086596 | 0.73 | RAB9A (0.64) | NPSR1RAB9APOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447422-A | Penicillins and compositions containing them | BEECHAM GROUP P.1.C. (GB) | 1984-05-08 | — | — | US | disclosed |
| EP-0067610-A1 | Penicillins, a process for their preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | disclosed |