Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.55 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.49 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17821260 | 1.00 | NOD1 (0.55) | NOD1GRIK1GRIK2GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL11537647 | 0.98 | NOD1 (0.53) | NOD1GRIK1GRIK2GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL2892786 | 0.98 | NOD1 (0.53) | NOD1GRIK1GRIK2GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL8203130 | 0.98 | NOD1 (0.53) | NOD1GRIK1GRIK2GNAI3GNAO1 | |
| SCHEMBL11296849 | 0.98 | NOD1 (0.52) | NOD1GRIK1GRIK2GNAI3GNAO1 | |
| SCHEMBL7247852 | 0.92 | NOD1 (0.50) | NOD1GRIK1GRIK2TP53CPB2 | |
| SCHEMBL27827672 | 0.92 | NOD1 (0.50) | NOD1GRIK1GRIK2TP53CPB2 | |
| SCHEMBL6589774 | 0.92 | NOD1 (0.50) | NOD1GRIK1GRIK2TP53CPB2 | |
| Hydrochloric Acid SCHEMBL6843156 | 0.90 | NOD1 (0.49) | NOD1GRIK1GRIK2TP53CPB2 | |
| Hydrochloric Acid SCHEMBL5906900 | 0.90 | NOD1 (0.49) | NOD1GRIK1GRIK2TP53CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486443-A | PROSTAGLANDIN-LIKE EFFECTS | BURROUGHS WELLCOME CO. (US) | 1984-12-04 | — | — | US | disclosed |
| US-4289707-A | Nitrogen heterocycles | BURROUGHS WELLCOME CO. (US) | 1981-09-15 | — | — | US | disclosed |
| US-4262128-A | HAVING PROSTAGLANDIN-LIKE BIOLOGICAL PROPERTIES | BURROUGHS WELLCOME CO. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4204068-A | Nitrogen heterocycles | BURROUGHS WELLCOME CO. (US) | 1980-05-20 | — | — | US | disclosed |