Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 2/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17821260 | 0.98 | NOD1 (0.55) | NOD1TP53OPRM1GRIK1GRIK2 | |
| SCHEMBL11083554 | 0.98 | NOD1 (0.55) | NOD1TP53OPRM1GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL11537647 | 0.96 | NOD1 (0.53) | NOD1TP53OPRM1GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL8203130 | 0.96 | NOD1 (0.53) | NOD1TP53OPRM1GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL2892786 | 0.96 | NOD1 (0.53) | NOD1TP53OPRM1GRIK1GRIK2 | |
| SCHEMBL7247852 | 0.94 | NOD1 (0.50) | NOD1TP53GRIK1GRIK2SLC1A2 | |
| SCHEMBL6589774 | 0.94 | NOD1 (0.50) | NOD1TP53GRIK1GRIK2SLC1A2 | |
| SCHEMBL27827672 | 0.94 | NOD1 (0.50) | NOD1TP53GRIK1GRIK2SLC1A2 | |
| Hydrochloric Acid SCHEMBL6843156 | 0.92 | NOD1 (0.49) | NOD1TP53GRIK1GRIK2SLC1A2 | |
| Hydrochloric Acid SCHEMBL5906900 | 0.92 | NOD1 (0.49) | NOD1TP53GRIK1GRIK2SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3932917-A2 | SUBSTITUTED PHENYLOXAZOLIDINONES FOR ANTIMICROBIAL THERAPY | The Global Alliance for TB Drug Development, Inc. (US) | 2022-01-05 | — | — | EP | disclosed |
| EP-3096751-B1 | 12-EPI-PLEUROMUTILINS | Nabriva Therapeutics GmbH (AT) | 2021-01-06 | — | — | EP | disclosed |
| CN-105916499-B | 12-epi-pleuromutilins | 纳布里瓦治疗股份公司 | 2020-02-18 | — | — | CN | disclosed |
| US-9701628-B2 | 12-epi pleuromutilins | NABRIVA THERAPEUTICS AG (AT) | 2017-07-11 | — | — | US | disclosed |
| EP-3096751-A1 | 12-EPI-PLEUROMUTILINS | Nabriva Therapeutics AG (AT) | 2016-11-30 | — | — | EP | disclosed |
| US-20160332963-A1 | 12-EPI PLEUROMUTILINS | Nabriva Therapeutics GmbH (AT) | 2016-11-17 | — | — | US | disclosed |
| WO-2015110481-A1 | 12-EPI-PLEUROMUTILINS | NABRIVA THERAPEUTICS AG (AT) | 2015-07-30 | — | — | WO | disclosed |
| CN-103588654-A | Method for synthesizing ethyl 3-n-butyl amino propionate | CHIEN SHIUNG INST TECHNOLOGY | 2014-02-19 | — | — | CN | disclosed |
| EP-1543983-B1 | Ink-jet recording medium and process for producing the same | FUJIFILM CORP (JP) | 2008-02-20 | — | — | EP | disclosed |
| US-4255319-A | PHOSPHINE INHIBITION; NONTOXIC; STORAGE STABILITY; MATERIALS HANDLING | UNION CARBIDE CORPORATION (US) | 1981-03-10 | — | — | US | disclosed |
| US-4014839-A | BIS(HYDROCARBYL)VINYL PHOSPHONATES | STAUFFER CHEMICAL COMPANY (US) | 1977-03-29 | — | — | US | disclosed |
| US-3992481-A | Fire retardant thermoplastic polymer compositions | STAUFFER CHEMICAL COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3992337-A | VINYL PHOSPHONATE - HALOGEN CONTAINING MONOMER COPOLYMER | STAUFFER CHEMICAL COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3992482-A | Fire retardant thermoplastic polymer compositions | STAUFFER CHEMICAL COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3991134-A | Fire retardant thermoplastic polymer compositions | STAUFFER CHEMICAL COMPANY (US) | 1976-11-09 | — | — | US | disclosed |
| US-3991142-A | FROM TRIS(2,3-DIBROMOPYL)PHOSPHITE WITH PHOSPHORIC ACID | STAUFFER CHEMICAL COMPANY (US) | 1976-11-09 | — | — | US | disclosed |
| US-3965216-A | BIS(HYDROCARBYL) VINYL PHOSPHONATE | STAUFFER CHEMICAL COMPANY (US) | 1976-06-22 | — | — | US | disclosed |
| US-3948842-A | Fire retardant polymeric additives of vinylidene halides with bis(hydrocarbyl) vinyl phosphonates and C1 -C20 alkylesters of acrylic and methacrylic acids | STAUFFER CHEMICAL COMPANY (US) | 1976-04-06 | — | — | US | disclosed |
| US-3943085-A | HYDROCARBYL VINYL PHOSPHONATE-VINYL OR VINYLIDENE HALIDE, FLAME RETARDANT | STAUFFER CHEMICAL COMPANY (US) | 1976-03-09 | — | — | US | disclosed |
| US-3935149-A | BIS(HYDROCARBYL) VINYL PHOSPHONATE, VINYL OR VINYLIDENE HALIDE | STAUFFER CHEMICAL COMPANY (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160332963-A1 | 12-EPI PLEUROMUTILINS | MLN, TCF12, PLEC | NOD1 3630/4885TP53 1607/4885OPRM1 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.