Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 5/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11581904 | 0.87 | CYP1A2 (0.37) | CYP1A2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL27535979 | 0.85 | ALDH1A1 (0.36) | ALDH1A1ATMMEN1KMT2APOLB | |
| SCHEMBL4098881 | 0.81 | RAB9A (0.49) | CYP1A2ALDH1A1ATMNPC1KDM4E | |
| SCHEMBL4107483 | 0.81 | MEN1 (0.56) | CYP1A2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL5529517 | 0.81 | CYP1A2 (0.44) | CYP1A2ALDH1A1ATMMEN1KMT2A | |
| SCHEMBL30499691 | 0.81 | CYP1A2 (0.44) | CYP1A2ALDH1A1ATMMEN1KMT2A | |
| SCHEMBL11578653 | 0.79 | KMT2A (0.48) | CYP1A2KMT2AMAPT | |
| SCHEMBL11579747 | 0.79 | RAB9A (0.51) | CYP1A2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11581052 | 0.79 | MAPK1 (0.51) | CYP1A2ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11578740 | 0.79 | CYP1A2 (0.43) | CYP1A2ALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446152-A | SUBSTITUTED PHENYLAMIDINOUREA | WILLIAM H. RORER, INC. (US) | 1984-05-01 | — | — | US | disclosed |
| US-4088785-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1978-05-09 | — | — | US | disclosed |