Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9939509 | 0.92 | TSHR (0.39) | KDM4ERAB9ALMNAALDH1A1MEN1 | |
| SCHEMBL19010647 | 0.79 | TSHR (0.39) | KDM4EGAASMN1; SMN2TSHRJAK2 | |
| SCHEMBL12226437 | 0.77 | KDM4E (0.51) | KDM4ERAB9ALMNAALDH1A1MEN1 | |
| SCHEMBL11079865 | 0.77 | KDM4E (0.51) | KDM4ERAB9ALMNAALDH1A1MEN1 | |
| SCHEMBL2663389 | 0.76 | SMN1; SMN2 (0.51) | RAB9AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9148809 | 0.76 | TSHR (0.36) | KDM4ESMN1; SMN2TSHR | |
| SCHEMBL9148812 | 0.76 | TSHR (0.36) | KDM4ESMN1; SMN2TSHR | |
| SCHEMBL9148823 | 0.76 | TSHR (0.36) | KDM4ESMN1; SMN2TSHR | |
| SCHEMBL10774433 | 0.75 | TSHR (0.48) | KDM4ELMNAMEN1KMT2AGAA | |
| SCHEMBL16199661 | 0.74 | JAK2 (0.38) | SMN1; SMN2POLBTSHRJAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432985-A | N-alkylated carboxylic acid derivatives as anti-convulsant agents | ABBOTT LABORATORIES (US) | 1984-02-21 | — | — | US | disclosed |