Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765358 | 0.91 | — | — | |
| SCHEMBL12226437 | 0.82 | KDM4E (0.51) | KDM4ERAB9ALMNAALDH1A1MEN1 | |
| SCHEMBL11080389 | 0.81 | HSD17B10 (0.41) | KDM4ERAB9ALMNAALDH1A1MEN1 | |
| SCHEMBL21675650 | 0.78 | HSD17B10 (0.45) | KDM4ERAB9ALMNAALDH1A1MEN1 | |
| SCHEMBL2557014 | 0.78 | L3MBTL1 (0.42) | KDM4ERAB9ALMNAALDH1A1POLB | |
| SCHEMBL11084180 | 0.77 | KDM4E (0.47) | KDM4ERAB9ALMNAALDH1A1MEN1 | |
| SCHEMBL14671158 | 0.76 | HSD17B10 (0.41) | ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL8406208 | 0.76 | POLB (0.49) | KDM4ERAB9ALMNAALDH1A1MEN1 | |
| SCHEMBL7289985 | 0.76 | POLB (0.49) | KDM4ERAB9ALMNAALDH1A1MEN1 | |
| SCHEMBL15447586 | 0.76 | POLB (0.49) | KDM4ERAB9ALMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432985-A | N-alkylated carboxylic acid derivatives as anti-convulsant agents | ABBOTT LABORATORIES (US) | 1984-02-21 | — | — | US | claimed |
| US-4432985-A | N-alkylated carboxylic acid derivatives as anti-convulsant agents | ABBOTT LABORATORIES (US) | 1984-02-21 | — | — | US | disclosed |