Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5985980 | 0.89 | MAPT (0.57) | MAPTRXFP1MEN1KMT2AALDH1A1 | |
| SCHEMBL29769204 | 0.89 | MAPT (0.57) | MAPTRXFP1MEN1KMT2AALDH1A1 | |
| SCHEMBL3481207 | 0.85 | BRPF1 (0.62) | BRPF1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL31036167 | 0.85 | BRPF1 (0.62) | BRPF1MAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27614396 | 0.83 | BRPF1 (0.61) | BRPF1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL12182 | 0.77 | RXFP1 (0.53) | BRPF1MAPTRXFP1MEN1KMT2A | |
| SCHEMBL18000199 | 0.73 | BRPF1 (0.52) | BRPF1MAPTRXFP1MEN1KMT2A | |
| SCHEMBL5986735 | 0.72 | MAPT (0.52) | MAPTRXFP1MEN1KMT2AALDH1A1 | |
| SCHEMBL11084698 | 0.71 | KMT2A (0.41) | BRPF1MAPTRXFP1MEN1KMT2A | |
| SCHEMBL26435742 | 0.71 | CYP1A2 (0.44) | MAPTRXFP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443615-A | ANILINE, GLYCOL OR EPOXIDE, SILICA AND/OR ALUMINA CATALYST | TANABE SEIYAKU CO., LTD. (JP) | 1984-04-17 | — | — | US | disclosed |