SCHEMBL5986735

SCHEMBL5986735

Cc1ccc2cc(C)n(C)c2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.52
RXFP1 Q9HBX9 1/20 0.52
CYP2A6 P11509 3/20 0.46
CYP1A2 P05177 3/20 0.46
MEN1 O00255 7/20 0.40
KMT2A Q03164 7/20 0.40
ALDH1A1 P00352 4/20 0.40
THRB P10828 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
KMO O15229 1/20 0.37
NR1I2 O75469 1/20 0.36
AHR P35869 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
PDE2A O00408 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5985980 0.82 MAPT (0.57) MAPTRXFP1CYP2A6CYP1A2MEN1
SCHEMBL29769204 0.82 MAPT (0.57) MAPTRXFP1CYP2A6CYP1A2MEN1
SCHEMBL10222171 0.78 PSMB8 (0.42) MAPTCYP2A6MEN1KMT2AALDH1A1
SCHEMBL18000416 0.78 MCL1 (0.40) MAPTRXFP1CYP2A6MEN1KMT2A
SCHEMBL18000385 0.78 MAPT (0.40) MAPTRXFP1CYP2A6CYP1A2MEN1
SCHEMBL5246480 0.78 MEN1 (0.45) MAPTRXFP1CYP1A2MEN1KMT2A
SCHEMBL18000199 0.78 BRPF1 (0.52) MAPTRXFP1CYP2A6MEN1KMT2A
SCHEMBL17427791 0.78 MEN1 (0.42) MAPTCYP1A2MEN1KMT2AALDH1A1
SCHEMBL18000435 0.77 FGFR1 (0.36) MAPTRXFP1MEN1KMT2AALDH1A1
SCHEMBL18177589 0.76 MEN1 (0.39) MAPTCYP1A2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263760-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-08-21 US disclosed
US-12319946-B2 Methods for producing modified bacteria for production of nitroaromatics UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-06-03 US disclosed
US-20240229090-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-07-11 US disclosed
US-20240229090-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-07-11 US disclosed
US-20240229090-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-07-11 US disclosed
US-20240074303-A1 DISPLAY APPARATUS SAMSUNG DISPLAY CO., LTD. (KR) 2024-02-29 US disclosed
US-11879144-B2 Modified bacteria for production of nitroaromatics UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-01-23 US disclosed
EP-3647311-B1 RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF BEIJING TIDE PHARMACEUTICAL CO LTD (CN) 2023-11-01 EP disclosed
US-20230287466-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH (US) 2023-09-14 US disclosed
US-20230287466-A1 MODIFIED BACTERIA FOR PRODUCTION OF NITROAROMATICS UNIVERSITY OF FLORIDA RESEARCH (US) 2023-09-14 US disclosed
WO-2010150840-A1 N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE 大日本住友製薬株式会社 (JP) 2010-12-29 WO disclosed
US-20100308312-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308312-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
EP-2243779-A1 BICYCLIC HETEROCYCLIC DERIVATIVE Dainippon Sumitomo Pharma Co., Ltd. (JP) 2010-10-27 EP disclosed
US-20090189058-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2009-07-30 US disclosed
US-20090189058-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2009-07-30 US disclosed
US-20090085029-A1 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20090085029-A1 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
US-20080167476-A1 Process for the preparation of 2-substituted-7-Boryl indoles and compounds BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2008-07-10 US disclosed
US-7314580-B2 Compound, liquid-crystal composition and optical material FUJIFILM CORPORATION (JP) 2008-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080167476-A1 Process for the preparation of 2-substituted-7-Boryl indoles and compounds INMT, IDO2, IDO1 MAPT 3454/4885RXFP1 4043/4885CYP2A6 634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.