Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 3/20 | 0.53 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1354 | 0.93 | CA1 (0.46) | ACP3ALDH1A1L3MBTL1NPC1MAPT | |
| SCHEMBL857 | 0.84 | IDO1 (0.39) | NPSR1 | |
| SCHEMBL17616547 | 0.82 | ACP3 (0.49) | ACP3PBRM1CA4ALDH1A1NR3C1 | |
| SCHEMBL78901 | 0.79 | ACP3 (0.56) | ACP3PBRM1CA4ALDH1A1NR3C1 | |
| SCHEMBL17599983 | 0.79 | ACP3 (0.56) | ACP3PBRM1CA4ALDH1A1NR3C1 | |
| SCHEMBL9186560 | 0.78 | ACP3 (0.56) | ACP3PBRM1CA4ALDH1A1LTA4H | |
| SCHEMBL5536659 | 0.78 | IDO1 (0.45) | ALDH1A1NPSR1 | |
| SCHEMBL5537747 | 0.78 | IDO1 (0.58) | MAPTNPSR1CNR1TP53KMT2A | |
| SCHEMBL8716433 | 0.76 | RAB9A (0.46) | ACP3ALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL11784757 | 0.76 | ACP3 (0.58) | ACP3PBRM1CA4ALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4458071-A | Process for 1-oxa-β-lactams | ELI LILLY AND COMPANY (US) | 1984-07-03 | — | — | US | disclosed |
| EP-0109302-A1 | Process for 1-oxa-beta-lactams | ELI LILLY AND COMPANY (US) | 1984-05-23 | — | — | EP | disclosed |