Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772264 | 0.85 | CA2 (0.59) | CA2CA1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30709677 | 0.84 | CA2 (0.58) | CA2CA1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9008246 | 0.83 | ESR1 (0.59) | CA2CA1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL284652 | 0.82 | CA2 (0.58) | CA2CA1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11084650 | 0.81 | CYP3A4 (0.57) | CA2CA1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7515742 | 0.80 | CYP1A2 (0.50) | CA2CA1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15232928 | 0.78 | CA1 (0.52) | CA2CA1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL834546 | 0.76 | CA1 (0.61) | CA2CA1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8849761 | 0.76 | CA2 (0.66) | CA2CA1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL10024149 | 0.76 | CA1 (0.44) | CA2CA1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482728-A | ANTIFERTILITY AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1984-11-13 | — | — | US | disclosed |
| US-4357344-A | Polybutylbenzylphenols and benzyl-3,4-methylenedioxybenzenes in insect population control | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1982-11-02 | — | — | US | disclosed |
| US-4342777-A | GROWTH INHIBITOR FOR MOSQUITO LARVAE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1982-08-03 | — | — | US | disclosed |