SCHEMBL30709677

SCHEMBL30709677

COc1ccc([C@@H](O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.58
CA1 P00915 2/20 0.58
ALDH1A1 P00352 5/20 0.44
TSHR P16473 2/20 0.44
GAA P10253 2/20 0.44
LMNA P02545 2/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPT P10636 1/20 0.44
PKM P14618 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
HSD17B10 Q99714 1/20 0.44
BRD4 O60885 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
ELANE P08246 1/20 0.42
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8772264 0.85 CA2 (0.59) CA2CA1ALDH1A1TSHRGAA
SCHEMBL11084381 0.84 CA2 (0.58) CA2CA1ALDH1A1TSHRGAA
SCHEMBL30709668 0.81 CA2 (0.53) CA2CA1ALDH1A1TSHRGAA
SCHEMBL11210107 0.80 CA1 (0.45) CA2CA1ALDH1A1TSHRGAA
SCHEMBL30709713 0.80 TSHR (0.50) CA2CA1ALDH1A1TSHRGAA
SCHEMBL9136246 0.80 TSHR (0.50) CA2CA1ALDH1A1TSHRGAA
SCHEMBL120187 0.78 CA12 (0.58) CA2CA1ALDH1A1TSHRGAA
SCHEMBL30709609 0.77 HSPA5 (0.46) CA2CA1ALDH1A1TSHRGAA
SCHEMBL8849761 0.76 CA2 (0.66) CA2CA1ALDH1A1GAACYP2C9
SCHEMBL30641457 0.75 ALDH1A1 (0.51) CA2CA1ALDH1A1TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116903773-A Preparation method of polymer composite copper catalytic material and application of polymer composite copper catalytic material in synthesis of chiral gem diaryl borate 湖北工程学院 2023-10-20 CN disclosed