Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | PPOX | P50336 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083138 | 0.96 | TDP1 (0.46) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11086226 | 0.94 | TDP1 (0.48) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11091333 | 0.90 | RAB9A (0.35) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11087944 | 0.87 | TDP1 (0.53) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11192973 | 0.83 | ALDH1A1 (0.54) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11091007 | 0.82 | TDP1 (0.49) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11080021 | 0.81 | TDP1 (0.47) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11087948 | 0.81 | RAB9A (0.39) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11081834 | 0.80 | TDP1 (0.51) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11081725 | 0.79 | TDP1 (0.47) | TDP1MEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478634-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1984-10-23 | — | — | US | disclosed |
| US-4402729-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1983-09-06 | — | — | US | disclosed |