SCHEMBL11084875

SCHEMBL11084875

O=C1NC[C@H](c2ccccc2)[C@@H]1c1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 17/20 0.81
SLC6A2 P23975 13/20 0.69
SLC6A4 P31645 5/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11084872 1.00 SLC6A3 (0.81) SLC6A3SLC6A2SLC6A4
SCHEMBL11084869 1.00 SLC6A3 (0.81) SLC6A3SLC6A2SLC6A4
SCHEMBL11092197 0.90 SLC6A3 (0.72) SLC6A3SLC6A2SLC6A4
SCHEMBL11111638 0.90 SLC6A3 (0.72) SLC6A3SLC6A2SLC6A4
SCHEMBL31478305 0.90 SLC6A3 (1.00) SLC6A3SLC6A2SLC6A4
SCHEMBL11090847 0.90 SLC6A3 (0.72) SLC6A3SLC6A2SLC6A4
SCHEMBL11089310 0.87 SLC6A3 (0.68) SLC6A3SLC6A2SLC6A4
SCHEMBL11088626 0.86 SLC6A3 (0.67) SLC6A3SLC6A2SLC6A4
SCHEMBL10671944 0.81 SLC6A3 (0.57) SLC6A3SLC6A2SLC6A4
SCHEMBL11087875 0.79 PDE4A (0.67) SLC6A3SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4443616-A Production of 3-pyrrolin-2-ones THE PURDUE FREDERICK COMPANY (US) 1984-04-17 US disclosed