Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617961 | 0.89 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2AKR1B1RAB9A | |
| SCHEMBL4008419 | 0.88 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2AKR1B1RAB9A | |
| SCHEMBL11617346 | 0.88 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2AKR1B1RAB9A | |
| SCHEMBL11208417 | 0.87 | AKR1B1 (0.56) | ALDH1A1MAPTSMN1; SMN2AKR1B1RAB9A | |
| SCHEMBL11603832 | 0.87 | AKR1B1 (0.59) | ALDH1A1MAPTSMN1; SMN2AKR1B1RAB9A | |
| SCHEMBL11604179 | 0.87 | MAPT (0.51) | ALDH1A1MAPTSMN1; SMN2AKR1B1RAB9A | |
| SCHEMBL16689873 | 0.86 | ALDH1A1 (0.57) | ALDH1A1MAPTSMN1; SMN2AKR1B1RAB9A | |
| SCHEMBL11604322 | 0.85 | AKR1B1 (0.57) | ALDH1A1MAPTSMN1; SMN2AKR1B1RAB9A | |
| SCHEMBL11120325 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2AKR1B1RAB9A | |
| SCHEMBL246197 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPTSMN1; SMN2AKR1B1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082850-A | TOPICAL APPLICATION OF A 6,11-DIHYDROBENZ(B,E)OXEPIN-ALKANOIC ACID OR DERIVATIVES THEREOF | AMERICAN HOECHST CORPORATION (US) | 1978-04-04 | — | — | US | claimed |
| JP-55000380-A | — | — | None | — | — | JP | disclosed |
| US-4448786-A | TREATMENT AND PREVENTION OF CALCIUM OXALATE KIDNEY STONES | MERCK & CO., INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4349561-A | 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase | MERCK & CO., INC. (US) | 1982-09-14 | — | — | US | disclosed |
| JP-S55380-A | PREPARATION OF DIBENZOXEPIN DERIVATIVE | DAI ICHI SEIYAKU CO LTD | 1980-01-05 | — | — | JP | disclosed |