SCHEMBL11085201

SCHEMBL11085201

Nc1ccc(S(=O)(=O)Nc2ccc(N)c(Cl)c2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.60
HTR6 P50406 3/20 0.59
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
HTT P42858 1/20 0.58
CA9 Q16790 1/20 0.58
FFAR4 Q5NUL3 2/20 0.56
FFAR1 O14842 1/20 0.56
KMT2A Q03164 2/20 0.56
KEAP1 Q14145 1/20 0.56
CDC7 O00311 1/20 0.54
EEF2K O00418 1/20 0.54
PLK4 O00444 1/20 0.54
AURKA O14965 1/20 0.54
DYRK3 O43781 1/20 0.54
RPS6KA5 O75582 1/20 0.54
PRKD3 O94806 1/20 0.54
MAP4K4 O95819 1/20 0.54
PIM1 P11309 1/20 0.54
PHKG2 P15735 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23093373 0.89 PRMT1 (0.62) PRMT1HTR6CA1CA2HTT
SCHEMBL23093601 0.84 PKM (0.61) PRMT1HTR6CA1CA2HTT
SCHEMBL21497062 0.84 PRMT1 (0.61) PRMT1HTR6CA1CA2HTT
SCHEMBL28557305 0.83 HTR6 (0.63) PRMT1HTR6CA1CA2HTT
SCHEMBL23109220 0.81 CDC7 (0.58) PRMT1HTR6CA1CA2HTT
SCHEMBL5225275 0.81 CES1 (0.66) PRMT1CA1CA2HTTCA9
SCHEMBL540915 0.80 CA1 (0.85) PRMT1HTR6CA1CA2HTT
SCHEMBL11793140 0.80 CA1 (0.85) PRMT1HTR6CA1CA2HTT
SCHEMBL11096707 0.80 KMT2A (0.56) HTTFFAR4FFAR1KMT2AMAPT
SCHEMBL11083018 0.80 FFAR4 (0.67) CA1CA2HTTCA9FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4479906-A BLACK LEATHER DYE BASF AKTIENGESELLSCHAFT (DE) 1984-10-30 US disclosed