Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | CDC25C | P30307 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | GMNN | O75496 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20913014 | 0.93 | CDC25B (0.57) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL854153 | 0.81 | CDC25B (0.60) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL30716618 | 0.80 | KMT2A (0.54) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL20897263 | 0.80 | KMT2A (0.54) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL697232 | 0.78 | CDC25B (0.63) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL10595457 | 0.78 | PTPN1 (0.57) | CDC25BALDH1A1KDM4EHPGDPTPN1 | |
| SCHEMBL22062251 | 0.77 | CDC25B (0.61) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL11087897 | 0.77 | KMT2A (0.51) | ALDH1A1KDM4EHPGDPTPN1MEN1 | |
| SCHEMBL4910288 | 0.76 | CDC25B (0.60) | CDC25BALDH1A1KDM4ECDC25ACDC25C | |
| SCHEMBL5857951 | 0.75 | PTPN1 (0.71) | CDC25BALDH1A1KDM4EHPGDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4471129-A | ANTIHISTAMINES | LILLY INDUSTRIES LIMITED (GB) | 1984-09-11 | — | — | US | disclosed |
| US-4448787-A | ANTIALLERGENS | LILLY INDUSTRIES LIMITED (GB) | 1984-05-15 | — | — | US | disclosed |
| US-4304728-A | 2,6-DIHYDROXY-2,5-HEXADIENOIC ACID DERIVATIVES, ANTIHISTAMINE INTERMEDIATES | LILLY INDUSTRIES LIMITED (GB) | 1981-12-08 | — | — | US | disclosed |