SCHEMBL4910288

SCHEMBL4910288

C=C(C(=O)OCC)c1cccc2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 2/20 0.60
CDC25A P30304 1/20 0.52
CDC25C P30307 1/20 0.52
ALDH1A1 P00352 4/20 0.52
KDM4E B2RXH2 2/20 0.52
HPGD P15428 2/20 0.50
TSHR P16473 2/20 0.47
NR4A1 P22736 1/20 0.47
NR4A2 P43354 1/20 0.47
NR4A3 Q92570 1/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
MAPT P10636 2/20 0.46
PTPN1 P18031 1/20 0.46
PLK1 P53350 1/20 0.46
CA12 O43570 1/20 0.46
CA2 P00918 1/20 0.46
CA9 Q16790 1/20 0.46
PTK2B Q14289 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28989655 0.87 ALDH1A1 (0.50) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL27798501 0.85 ALDH1A1 (0.59) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL697232 0.84 CDC25B (0.63) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL2777501 0.83 CNR2 (0.47) CDC25BALDH1A1KDM4EHPGDTSHR
SCHEMBL22062251 0.83 CDC25B (0.61) CDC25BCDC25ACDC25CALDH1A1KDM4E
SCHEMBL3794319 0.82 PLK1 (0.54) CDC25BALDH1A1KDM4EHPGDTSHR
SCHEMBL2777499 0.82 NR4A1 (0.45) CDC25BALDH1A1KDM4EHPGDTSHR
SCHEMBL9696983 0.82 CYP3A4 (0.53) CDC25BALDH1A1KDM4EHPGDTSHR
SCHEMBL27648071 0.82 NR4A1 (0.45) CDC25BALDH1A1KDM4EHPGDTSHR
SCHEMBL28989610 0.81 KMT2A (0.48) CDC25BCDC25ACDC25CALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050069637-A1 Method for manufacturing planar optical waveguide KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2005-03-31 US claimed
CN-116981758-A Thermally responsive brush polymers having a copolymer backbone and copolymer arms 英菲诺姆国际有限公司 2023-10-31 CN disclosed
CN-115989251-A Composition comprising an additive having polycyclic aromatic groups 伊英克公司 2023-04-18 CN disclosed
CN-112367983-A 1,4 substituted isoquinoline inhibitors of KEAP1/NRF2 protein-protein interaction 伊利诺伊大学评议会 2021-02-12 CN disclosed
EP-1791901-B1 STABILIZATION OF ORGANIC MATERIALS BASF SE (DE) 2018-03-28 EP disclosed
EP-1791901-B1 STABILIZATION OF ORGANIC MATERIALS BASF SE (DE) 2018-03-28 EP disclosed
US-9051448-B2 Stabilization of organic materials BASF SE (DE) 2015-06-09 US disclosed
US-9051448-B2 Stabilization of organic materials BASF SE (DE) 2015-06-09 US disclosed
US-9051448-B2 Stabilization of organic materials BASF SE (DE) 2015-06-09 US disclosed
US-20080269382-A1 Stabilization of Organic Materials BASF SE (DE) 2008-10-30 US disclosed
WO-2001021600-A1 CASPASE INHIBITOR LG CHEM INVESTMENT LTD. (KR) 2001-03-29 WO disclosed
WO-2001021599-A1 CASPASE INHIBITOR LG CHEMICAL LTD. (KR) 2001-03-29 WO disclosed
US-6162822-A Bisimide compounds ADIR ET COMPAGNIE (FR) 2000-12-19 US disclosed
WO-2000061539-A1 3-BICYCLOARYL-2-AMINOMETHYL BICYCLOALKANES AS SEROTONINE REUPTAKE INHIBITORS ELI LILLY AND COMPANY LIMITED (GB) 2000-10-19 WO disclosed
US-6005116-A HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA SANKYO COMPANY, LIMITED (JP) 1999-12-21 US disclosed
US-5854273-A Bisimide compounds ADIR ET COMPAGNIE (FR) 1998-12-29 US disclosed
EP-0885891-A1 ISOXAZOLE DERIVATIVES SANKYO COMPANY LIMITED (JP) 1998-12-23 EP disclosed
EP-0040177-B1 PROCESS FOR THE PREPARATION OF BENZENE OR NAPHTHALENE ALKENYL CARBOXYLIC ACID DERIVATIVES CIBA-GEIGY AG (CH) 1983-07-20 EP disclosed
US-4335054-A Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives CIBA-GEIGY CORPORATION (US) 1982-06-15 US disclosed
WO-1980001978-A1 SOLID STATE DEVICES BY DIFFERENTIAL PLASMA ETCHING OF RESISTS WESTERN ELECTRIC CO (US) 1980-09-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080269382-A1 Stabilization of Organic Materials LPO, PPOX, HMOX1 CDC25B 1105/4885CDC25A 309/4885CDC25C 1070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.