Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 8/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 11/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11266029 | 0.89 | MT-CO2 (0.43) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11082982 | 0.86 | AKR1C3 (0.44) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11089935 | 0.84 | ALPG (0.46) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11083819 | 0.82 | ALPG (0.47) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11088552 | 0.80 | KDM4E (0.45) | ALPGPTAFRTBXAS1AKR1B1 | |
| SCHEMBL11082035 | 0.80 | AKR1C3 (0.39) | AKR1B1 | |
| SCHEMBL11076242 | 0.79 | ALPG (0.64) | ALPGPTAFRTBXAS1AKR1B1 | |
| SCHEMBL11084425 | 0.79 | ALPG (0.46) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11090785 | 0.79 | KDM4E (0.48) | ALPGPTAFRTBXAS1 | |
| SCHEMBL11085356 | 0.78 | AKR1B1 (0.38) | PTAFRTBXAS1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0011142-B1 | PYRIDO (2,1-B) QUINAZOLINONES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-12-29 | — | — | EP | claimed |
| EP-0011142-A1 | Pyrido (2,1-b) quinazolinones, their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-05-28 | — | — | EP | claimed |
| US-4457927-A | Pyrido[2,1-b]quinazolinone derivatives and the preparation and use thereof | SCHERING, AKTIENGESELLSCHAFT (DE) | 1984-07-03 | — | — | US | disclosed |
| EP-0011142-A1 | Pyrido (2,1-b) quinazolinones, their preparation and pharmaceutical compositions containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-05-28 | — | — | EP | disclosed |