Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 11/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 11/20 | 0.46 |
| ▸ | PTAFR | P25105 | 5/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11082982 | 0.85 | AKR1C3 (0.44) | AKR1C3AKR1C2PTAFRALPGTBXAS1 | |
| SCHEMBL11079315 | 0.82 | AKR1C3 (0.45) | AKR1C3AKR1C2PTAFRALPGTBXAS1 | |
| SCHEMBL11090785 | 0.80 | KDM4E (0.48) | PTAFRALPGTBXAS1 | |
| SCHEMBL11084425 | 0.78 | ALPG (0.46) | PTAFRALPGTBXAS1 | |
| SCHEMBL11083819 | 0.77 | ALPG (0.47) | PTAFRALPGTBXAS1 | |
| SCHEMBL11085352 | 0.76 | ALPG (0.40) | PTAFRALPGTBXAS1 | |
| SCHEMBL11089935 | 0.76 | ALPG (0.46) | PTAFRALPGTBXAS1 | |
| SCHEMBL11082635 | 0.76 | MAOA (0.41) | AKR1C3AKR1C2CHRM1PTGS1 | |
| SCHEMBL11259134 | 0.76 | KDM4E (0.53) | PTAFRALPGTBXAS1PTGS1 | |
| SCHEMBL11076242 | 0.76 | ALPG (0.64) | PTAFRALPGTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457927-A | Pyrido[2,1-b]quinazolinone derivatives and the preparation and use thereof | SCHERING, AKTIENGESELLSCHAFT (DE) | 1984-07-03 | — | — | US | disclosed |