Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.43 |
| ▸ | CHRNG | P07510 | 1/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11083245 | 0.85 | MDM2 (0.52) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL634167 | 0.81 | SLC6A2 (0.49) | KCNH2MEN1KMT2AERCC5FEN1 | |
| SCHEMBL4741238 | 0.79 | PARP1 (0.50) | KCNH2MEN1KMT2AERCC5FEN1 | |
| SCHEMBL28631032 | 0.79 | PARP1 (0.50) | KCNH2MEN1KMT2AERCC5FEN1 | |
| SCHEMBL634150 | 0.78 | ALDH1A1 (0.51) | KCNH2ERCC5FEN1MAPTSLC6A2 | |
| SCHEMBL633919 | 0.77 | SLC6A2 (0.51) | KCNH2MEN1KMT2AERCC5FEN1 | |
| SCHEMBL634447 | 0.77 | ALDH1A1 (0.50) | KCNH2SLC6A2CHRNA1CHRNGITGA5 | |
| SCHEMBL12495745 | 0.77 | KCNJ5 (0.45) | KCNH2MEN1KMT2AERCC5FEN1 | |
| SCHEMBL17492409 | 0.77 | PARP1 (0.45) | KCNH2ERCC5FEN1SLC6A2CHRNA1 | |
| SCHEMBL634064 | 0.76 | ALDH1A1 (0.49) | KCNH2SLC6A2CHRNA1CHRNGITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431648-A | ANTIDEPRESSANTSD | SYNTHELABO (FR) | 1984-02-14 | — | — | US | disclosed |