Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 2/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19104774 | 0.89 | RAB9A (0.51) | MDM2HPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11085580 | 0.85 | METAP2 (0.52) | KMT2ASMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL1303851 | 0.85 | NPC1 (0.60) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6248066 | 0.82 | CNR2 (0.49) | HPGDKMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL5870056 | 0.82 | CNR2 (0.49) | HPGDKMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL4061138 | 0.82 | CNR2 (0.49) | HPGDKMT2ASMN1; SMN2MEN1HTT | |
| SCHEMBL4257686 | 0.81 | MDM2 (0.66) | MDM2KMT2AMEN1TDP1CTRB1 | |
| SCHEMBL5214256 | 0.81 | GSK3B (0.47) | MDM2HPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9768627 | 0.79 | MAPK1 (0.45) | MDM2HPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8472563 | 0.79 | ERAP1 (0.49) | HPGDKMT2ASMN1; SMN2MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431648-A | ANTIDEPRESSANTSD | SYNTHELABO (FR) | 1984-02-14 | — | — | US | disclosed |