Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.38 |
| ▸ | HMGCR | P04035 | 2/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10927069 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7527151 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL1279585 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7527108 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9052855 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL22160255 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL23647759 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL18037106 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL887761 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL887750 | 1.00 | TSHR (0.44) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042270-B1 | LUBRICATING OIL ADDITIVE, METHOD FOR MAKING THE SAME, LUBRICATING OIL ADDITIVE PACKAGE, AND LUBRICATING OIL COMPOSITION COMPRISING THE SAME, AND THE USE OF CERTAIN SUCCINIMIDES IN FORMING OIL ADDITIVES | EDWIN COOPER INC. (US) | 1984-09-12 | — | — | EP | disclosed |
| WO-1983003616-A1 | FUEL AND LUBRICATING COMPOSITIONS CONTAINING N-HYDROXYMETHYL SUCCINIMIDES | COOPER EDWIN INC (US) | 1983-10-27 | — | — | WO | disclosed |
| US-4325827-A | FRICTION RESISTANCE | EDWIN COOPER, INC. (US) | 1982-04-20 | — | — | US | disclosed |
| EP-0042270-A2 | Lubricating oil additive, method for making the same, lubricating oil additive package, and lubricating oil composition comprising the same, and the use of certain succinimides in forming oil additives | EDWIN COOPER INC. (US) | 1981-12-23 | — | — | EP | disclosed |
| US-4295983-A | Lubricating oil composition containing boronated N-hydroxymethyl succinimide friction reducers | ETHYL CORPORATION (US) | 1981-10-20 | — | — | US | disclosed |