SCHEMBL887761

SCHEMBL887761

CCCCCCCCCCCCCC/[C]=C\CCCCCCCCCCCCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.40
FAAH O00519 2/20 0.39
TRPV1 Q8NER1 2/20 0.39
DNM1 Q05193 3/20 0.38
HMGCR P04035 2/20 0.36
EP300 Q09472 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10927069 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL7527151 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL1279585 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL7527108 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL9052855 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL22160255 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL23647759 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL18037106 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL11086709 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL887750 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2746372-B1 Additive compositions with plural friction modifiers AFTON CHEMICAL CORP (US) 2020-09-16 EP disclosed
US-9499763-B2 Additive compositions with plural friction modifiers AFTON CHEMICAL CORPORATION (US) 2016-11-22 US disclosed
US-20140179572-A1 ADDITIVE COMPOSITIONS WITH PLURAL FRICTION MODIFIERS AFTON CHEMICAL CORPORATION (US) 2014-06-26 US disclosed
EP-2746372-A1 Additive compositions with plural friction modifiers Afton Chemical Corporation (US) 2014-06-25 EP disclosed
US-8058214-B2 Process for making shock absorber fluid CHEVRON U.S.A. INC. (US) 2011-11-15 US disclosed
US-8022024-B2 Functional fluid compositions CHEVRON U.S.A. INC. (US) 2011-09-20 US disclosed
EP-1078977-B1 LUBRICANT COMPOSITIONS AFTON CHEMICAL LTD (GB) 2010-01-27 EP disclosed
WO-2009006259-A2 PROCESS FOR MAKING SHOCK ABSORBER FLUID CHEVRON U.S.A. INC. (US) 2009-01-08 WO disclosed
WO-2009006283-A2 FUNCTIONAL FLUID COMPOSITIONS CHEVRON U.S.A. INC. (US) 2009-01-08 WO disclosed
US-20090005275-A1 Power steering fluid CHEVRON U.S.A. INC. (US) 2009-01-01 US disclosed
US-5767045-A WEAR RESISTANT ADDITIVE OF ZINC DIHYDROCARBYL DITHIOPHOSPHATE AND ADDITIVE OF SUCCINIMIDE AND/OR SUCCINAMIDE-TYPE COMPOUND ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1998-06-16 US disclosed
EP-0776964-A1 Hydraulic fluids ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1997-06-04 EP disclosed
US-RE34459-E Friction modifier ETHYL PETROLEUM ADDITIVES, LIMITED (GB) 1993-11-30 US disclosed
EP-0389237-B1 FRICTION MODIFIER ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1993-05-05 EP disclosed
US-5190680-A Friction modifier comprising a long chain succinimide derivative and long chain acid amide ETHYL PETROLEUM ADDITIVES LTD. (GB) 1993-03-02 US disclosed
US-5126064-A For noise reduction in limited slip differentials ETHYL PETROLEUM ADDITIVES, LTD. (GB) 1992-06-30 US disclosed
EP-0399764-B1 LUBRICANT COMPOSITIONS ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1992-03-25 EP disclosed
US-5021176-A Friction modifier ETHYL PETROLEUM ADDITIVES, LIMITED (GB) 1991-06-04 US disclosed
EP-0399764-A1 Lubricant compositions ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1990-11-28 EP disclosed
EP-0389237-A2 Friction modifier ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1990-09-26 EP disclosed