SCHEMBL9052855

SCHEMBL9052855

CCCCCCCCCCCCCCCC/C=[C]/CCCCCCCCCCCCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.40
FAAH O00519 2/20 0.39
TRPV1 Q8NER1 2/20 0.39
DNM1 Q05193 3/20 0.38
HMGCR P04035 2/20 0.36
EP300 Q09472 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10927069 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL7527151 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL1279585 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL7527108 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL22160255 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL23647759 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL18037106 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL11086709 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL887761 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL887750 1.00 TSHR (0.44) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996036683-A1 MIXED PHOSPHOROUS- AND SULFUR-CONTAINING REACTION PRODUCTS USEFUL IN POWER TRANSMITTING COMPOSITIONS EXXON CHEMICAL PATENTS INC. (US) 1996-11-21 WO disclosed
US-5534170-A OXIDATION AND WEAR RESISTANCE; BETA-HYDROXY THIOETHER, ORGANOPHOSPHITE, AND HYDROXY NUCLEOPHILIC REACTANTS EXXON CHEMICAL PATENTS INC. (US) 1996-07-09 US disclosed
EP-0557285-B1 LOW PRESSURE DERIVED MIXED PHOSPHOROUS- AND SULFUR-CONTAINING REACTION PRODUCTS USEFUL IN POWER TRANSMITTING COMPOSITIONS AND PROCESS FOR PREPARING SAME EXXON CHEMICAL PATENTS INC (US) 1995-12-20 EP disclosed
EP-0611818-A1 Low pressure derived mixed phosphorous- and sulfur-containing reaction products useful in power transmitting compositions and process for preparing the same EXXON CHEMICAL PATENTS INC. (US) 1994-08-24 EP disclosed
US-5314633-A Reaction product of a phosphite ester, thioalkanol and heterodialkanol EXXON CHEMICAL PATENTS INC. (US) 1994-05-24 US disclosed
EP-0394381-B1 MIXED PHOSPHOROUS- AND SULFUR-CONTAINING REACTION PRODUCTS USEFUL IN POWER TRANSMITTING COMPOSITIONS EXXON CHEMICAL PATENTS INC (US) 1994-05-04 EP disclosed
US-5242612-A A mixture of phosphorus- and nonphosphorus products resulting from the reaction of a beta-hydroxy thioether and an organic phosphite; power transmission fluids; crankcase oils; oxidation, wear and friction resistance EXXON CHEMICAL PATENTS INC. (US) 1993-09-07 US disclosed
US-5185090-A Oil additives; reacting betahydroxy thioethers and phosphite esters; antiwear, antioxidants EXXON CHEMICAL PATENTS INC. (US) 1993-02-09 US disclosed
EP-0394381-A1 MIXED PHOSPHOROUS- AND SULFUR-CONTAINING REACTION PRODUCTS USEFUL IN POWER TRANSMITTING COMPOSITIONS. EXXON CHEMICAL PATENTS INC (US) 1990-10-31 EP disclosed
WO-1989012666-A1 MIXED PHOSPHOROUS- AND SULFUR-CONTAINING REACTION PRODUCTS USEFUL IN POWER TRANSMITTING COMPOSITIONS EXXON CHEMICAL PATENTS, INC. (US) 1989-12-28 WO disclosed