Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520001 | 0.75 | LMNA (0.31) | LMNA | |
| SCHEMBL11298974 | 0.73 | MEN1 (0.40) | LMNA | |
| SCHEMBL6873070 | 0.71 | — | — | |
| SCHEMBL11535309 | 0.69 | LMNA (0.34) | LMNA | |
| SCHEMBL10065866 | 0.69 | LMNA (0.51) | LMNA | |
| SCHEMBL11523501 | 0.67 | HDAC4 (0.35) | — | |
| SCHEMBL11360980 | 0.67 | — | — | |
| SCHEMBL3731792 | 0.65 | KDM4E (0.38) | LMNA | |
| SCHEMBL8627478 | 0.65 | KDM4E (0.38) | LMNA | |
| SCHEMBL3731789 | 0.64 | KDM4E (0.37) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172199-A | ISOOXACEPHALOSPORINS | BRISTOL-MYERS COMPANY (US) | 1979-10-23 | — | — | US | claimed |
| US-4171439-A | Antibacterial analogs of isocephalosporins | BRISTOL-MYERS COMPANY (US) | 1979-10-16 | — | — | US | claimed |
| US-4171438-A | 0-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1979-10-16 | — | — | US | claimed |
| US-4166905-A | ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1979-09-04 | — | — | US | claimed |
| US-4166906-A | ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1979-09-04 | — | — | US | claimed |
| US-4118566-A | Δ2,3 -1,4-Morpholine-2-carboxylic acid derivatives as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1978-10-03 | — | — | US | claimed |
| US-4113946-A | Δ2,3 -1,4-Morpholine-2-carboxylic acid derivatives as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1978-09-12 | — | — | US | claimed |
| US-4112230-A | Δ2,3 -1,4 Morpholine-2-carboxylic acid derivatives as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1978-09-05 | — | — | US | claimed |
| US-4461726-A | Desulfurization of penicillins to prepare azetidinones | HOFFMANN-LA ROCHE INC. (US) | 1984-07-24 | — | — | US | disclosed |
| US-4195021-A | 1,3-Disubstituted 2-azetidinone antibitotics | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| US-4179511-A | Antibacterial 3-(5-tetrazolyl) penam compounds | PFIZER INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4172199-A | ISOOXACEPHALOSPORINS | BRISTOL-MYERS COMPANY (US) | 1979-10-23 | — | — | US | disclosed |
| US-4171439-A | Antibacterial analogs of isocephalosporins | BRISTOL-MYERS COMPANY (US) | 1979-10-16 | — | — | US | disclosed |
| US-4171438-A | 0-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1979-10-16 | — | — | US | disclosed |
| US-4066832-A | ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1978-01-03 | — | — | US | disclosed |
| US-4065623-A | O-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4065622-A | O-2-Isocephem-4-carboxylic acid derivatives as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4013648-A | BETA-LACTAM ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
| US-4012383-A | BACTERICIDES | BRISTOL-MYERS COMPANY (US) | 1977-03-15 | — | — | US | disclosed |
| US-4011216-A | Δ2,3-0-2-Isocephem-4-carboxylic acid and derivatives thereof as antibacterial agents | BRISTOL-MYERS COMPANY (US) | 1977-03-08 | — | — | US | disclosed |