SCHEMBL11535309

SCHEMBL11535309

O=[C]C(C1=CCC=CC1)S(=O)(=O)O

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5367355 0.62
SCHEMBL6276092 0.59 SRC (0.50) LMNA
SCHEMBL9351225 0.58 ACP3 (0.39) LMNA
SCHEMBL9329549 0.58 SRC (0.50) LMNA
SCHEMBL9994695 0.58
SCHEMBL9348302 0.57 TOP2A (0.32)
SCHEMBL10774890 0.57 HDAC3 (0.37) LMNA
SCHEMBL9347642 0.57 GABBR2 (0.43) LMNA
SCHEMBL9347446 0.57 TSHR (0.43) LMNA
Sulfuric Acid SCHEMBL11338102 0.49

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4179511-A Antibacterial 3-(5-tetrazolyl) penam compounds PFIZER INC. (US) 1979-12-18 US disclosed
US-4143039-A ANTIBACTERIAL 3-(5-TETRAZOLYL)PENAM COMPOUNDS PFIZER INC. (US) 1979-03-06 US disclosed
US-4115385-A PENICILLINS PFIZER INC. (US) 1978-09-19 US disclosed