Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 9/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11077407 | 0.99 | RAB9A (0.43) | RAB9ANPC1L3MBTL1PTGS2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11074227 | 0.83 | ALDH1A1 (0.36) | KMT2A | |
| Hydrochloric Acid SCHEMBL11557076 | 0.81 | SMN1; SMN2 (0.44) | RAB9ANPC1L3MBTL1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL11562696 | 0.81 | CYP1A2 (0.47) | L3MBTL1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL11085775 | 0.81 | MAPK1 (0.34) | SMN1; SMN2KMT2A | |
| SCHEMBL11564908 | 0.80 | HDAC3 (0.35) | RAB9ANPC1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL11055302 | 0.79 | MEN1 (0.35) | RAB9ANPC1KMT2ANPSR1 | |
| SCHEMBL10612763 | 0.79 | PLAU (0.35) | RAB9ANPC1KMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL11088274 | 0.79 | GRIN2D (0.36) | RAB9ANPC1L3MBTL1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL11562331 | 0.79 | SMN1; SMN2 (0.44) | RAB9ANPC1SMN1; SMN2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440949-A | Amidinoureas | WILLIAM H. RORER, INC. (US) | 1984-04-03 | — | — | US | disclosed |
| US-4242339-A | PHENYL-3-ALKOXYAMIDINOUREAS AND SALTS | WILLIAM H. RORER, INC. (US) | 1980-12-30 | — | — | US | disclosed |
| US-4242337-A | PHENYL-3-ALKOXYAMIDINOUREA AND SALTS | WILLIAM H. RORER, INC. (US) | 1980-12-30 | — | — | US | disclosed |
| US-4242340-A | PHENYL-3-ALKOXYAMIDINOUREAS AND SALTS | WILLIAM H. RORER, INC. (US) | 1980-12-30 | — | — | US | disclosed |
| US-4242338-A | PHENYLCARBAMOYLAMIDINOUREA AND SALTS | WILLIAM H. RORER, INC. (US) | 1980-12-30 | — | — | US | disclosed |
| US-4218450-A | Method for treatment of gastrointestinal spasmodic disease conditions or symptoms in mammals | WILLIAM H. RORER, INC. (US) | 1980-08-19 | — | — | US | disclosed |
| US-4169155-A | AMIDINOUREAS | WILLIAM H. RORER, INC. (US) | 1979-09-25 | — | — | US | disclosed |
| US-4115647-A | ANTISECRETORY, ANTISPASMODIC, ANTIULCEROGENIC, ANTIDIARRHEAL | WILLIAM H. RORER, INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4058557-A | Amidinoureas | WILLIAM H. RORER, INC. (US) | 1977-11-15 | — | — | US | disclosed |